Jia Haiting,Sun Lihua,Liu Tao,et al.Clinical features of acute metaphyseal osteomyelitis involving epiphysis in children aged below 15 months and over 18 months[J].Journal of Clinical Pediatric Surgery,,():763-767.[doi:10.3760/cma.j.cn101785-202306036-011]
Clinical features of acute metaphyseal osteomyelitis involving epiphysis in children aged below 15 months and over 18 months
- Keywords:
- Osteomyelitis; Epiphyses; Signs and Symptoms; Pathology; Clinical; Child
- Abstract:
- Objective Epiphyseal and metaphyseal vascular channels usually disappear after 15-18 months.In this paper,the clinical characteristics of acute metaphyseal osteomyelitis involving epiphysis between 15 and 18 months of age were analyzed.Methods From July 2017 to October 2022,the relevant clinical data were retrospectively reviewed for 45 children with acute metaphyseal osteomyelitis involving epiphysis.Based upon age,12 children aged under 15 months were selected as observation group.There were 5 boys and 7 girls aged 19 days to 14 months.And 33 children aged over 18 months were designated as control group.There were 20 boys and 13 girls aged 19 months to 12 years.Gender,duration of onset,positive rate of pus culture,maximal body temperature at onset,inflammation index within 24h after admission,length of stay and presence or absence of arthritis were compared between two groups.Results No significant inter-group difference existed in gender (P>0.050).Maximal body temperature of observation and control groups was (38.78±0.69)℃ and (39.29±0.85)℃,median leukocyte 13.59×109/L and 12.98×109/L and median neutrophil 4.54×109/L and 8.57×109/L.Median C-reactive protein was 36.45 and 69.10 mg/L,erythrocyte sedimentation rate (59.75±20.63) and (70.97±24.34) mm/h and duration of onset (7.50±3.66) and (6.94±3.18) day.Median length of hospitalization was 30.0 and 32.0 day.There was no difference of statistical significance (P>0.050).Positive rate of pus culture in observation and control groups was 66.7% and 69.7%.There was no difference of statistical significance (P>0.050).Five cases in observation group and 22 in control group were complicated with arthritis.There was no difference of statistical significance (P>0.050).During follow-ups,hip dislocation (n=2) occurred in observation group and there were hip stiffness (n=1) and knee contracture (n=1) in control group.Conclusions Clinical features of acute metaphyseal osteomyelitis involving epiphysis under an age of 15 months are basically similar to those over an age of 18 months.
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Memo
收稿日期:2023-6-20。
基金项目:山东省儿童健康与疾病临床医学研究中心立项项目(RC006)
通讯作者:刘涛,Email:ltetyy@163.com