Zhang Hanwen,Qi Xinyu,Liu Haonan,et al.Changes and predictors for perioperative C-reactive protein in children with congenital scoliosis hemivertebral deformity[J].Journal of Clinical Pediatric Surgery,,():561-566.[doi:10.3760/cma.j.cn101785-202203078-010]
Changes and predictors for perioperative C-reactive protein in children with congenital scoliosis hemivertebral deformity
- Keywords:
- Scoliosis; Congenital; Orthopedic Procedures; Perioperative Period; C-Reactive Protein; Root Cause Analysis
- Abstract:
- Objective To explore the changes and predictors for perioperative C-reactive protein (CRP) in children with congenital scoliosis hemivertebral deformity and summarize the relevant clinical experiences.Methods From October 2020 to October 2021,the clinical data were reviewed for 101 children with congenital scoliosis hemivertebral deformity.Posterior hemivertebra resection and internal fixation were performed.Factors including age,gender,height,weight,Stamp score,blood glucose,fasting time,preoperative Cobb angle,correction rate,operated segment,osteotomy findings,operative duration and laboratory examinations were analyzed by linear regression.And the changes and predictors of CRP were examined during perioperative period.Results All operations were completed successfully.There were 43 boys and 58 girls with an age range of (6.4±3.5) years.Operative duration was (199.2±68.4) min with an average of 3 operated segments and scoliosis correction rate 90.6%.Multivariable linear regression analysis indicated that an elevated level of postoperative CRP was associated with age,preoperative Cobb angle,operative duration and number of operated segments.Operative segment ≥4,operative duration ≥157 min and preoperative Cobb angle ≥27°hinted at a higher level of CRP (all P<0.05).Conclusions Children with severe deformity,more fused levels and longer operative duration tend to carry a greater risk of a higher postoperative level of CRP.
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Memo
收稿日期:2022-03-25。
基金项目:北京市自然科学基金(L222095)和新疆维吾尔自治区重点研发任务专项项目(2023B03018)
通信作者:张学军,Email:zhang-x-j04@163.com