Hong Lanlan,Fan Jiajie,Qiu Yunxiang,et al.Related factors for postoperative neurologic abnormalities immediately after surgery with cardiopulmonary bypass for congenital heart disease[J].Journal of Clinical Pediatric Surgery,,():51-55.[doi:10.3760/cma.j.cn101785-202212032-010]
Related factors for postoperative neurologic abnormalities immediately after surgery with cardiopulmonary bypass for congenital heart disease
- Keywords:
- Congenital Heart Disease; Cardiopulmonary Bypass; Neurologic Abnormality; Surgical Procedures; Operative; Child
- Abstract:
- Objective To summarize the clinical characteristics of children with postoperative neurologic abnormalities immediately after surgery with cardiopulmonary bypass (CPB) for congenital heart disease (CHD) and explore the risk factors of postoperative severe neurologic abnormalities within 1 month after surgery.Methods From February 2016 to April 2020,retrospective analysis was performed for the clinical data of 73 children with neurologic abnormalities within 1 month after cardiac surgery with CPB.They were divided into two groups of severe and non-severe neurological abnormality.Risk factors included type of CHD,age,weight,CPB time,aortic cross-clamp time,cardiac intensive care unit (CICU) retention time and hospitalization stay were compared between two groups by SPSS 25.0 for statistical processing.Results Among them,15 cases developed severe neurological abnormalities.Logistic multivariate analyses indicated that prolonged CPB time (OR=1.014,95%CI:1.002-1.025),prolonged aortic cross-clamp time(OR=1.030,95%CI:1.001-1.059) and reintubation after weaning (OR=0.157,95%CI:0.037-0.669) were independent risk factors for severe neurological abnormalities.Conclusions Programmed nervous system monitoring and evaluation are essential for early recognizing neurologic abnormalities after cardiac surgery with CPB.Longer CPB time,aortic occlusion time and necessity for re-intubation are the independent risk factors for severe neurologic abnormalities immediately after surgery.
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Memo
收稿日期:2022-12-14。
基金项目:浙江省基础公益研究计划(LGF21H02004)
通讯作者:施珊珊,Email:sicu1@zju.edu.cn