Lin Yu,Wang Huanmin,Yang Shen,et al.Preliminary exploration of transcatheter arterial embolization for ruptured hepatoblastoma[J].Journal of Clinical Pediatric Surgery,,22():1109-1113.[doi:10.3760/cma.j.cn101785-202310011-003]
Preliminary exploration of transcatheter arterial embolization for ruptured hepatoblastoma
- Keywords:
- Hepatoblastoma; Rupture; Endovascular Procedures; Embolization; Therapeutic; Postoperative Complications; Therapy; Prognosis; Child
- Abstract:
- Objective To explore the application of transcatheter arterial embolization (TAE) for ruptured hepatoblastoma (HB).Methods From March 2021 to May 2023,clinical characteristics,laboratory examinations,imaging features and outcomes were retrospectively reviewed for 10 children with ruptured HB undergoing TAE.Results There were 1 boy and 9 girls with a median onset age of 21.5(13.3,45.3) months.The median tumor diameter at diagnosis was 13.0(10.8,15.3) cm.Alpha fetoprotein (AFP) was elevated at an initial diagnosis.And the median value of AFP was 443641(137598,877500) ng/ml.After rupture,hemoglobin and erythrocyte declined and the median trough value of hemoglobin was 69.0(56.3,85.8) g/L.According to the PRETEXT preoperative staging system,the stages Ⅱ (n=1),Ⅲ (n=7) and Ⅳ (n=2).The frequency of TAE was once (n=7) and twice (n=3).After TAE,9/10 cases achieved successful hemostasis.During a median follow-up period of 15.00(3.75,19.25) month,9 patients survived and 1 died.Conclusions HB rupture is quite rare and difficult to treat.There are a heavy tumor burden,poor general status and a progressive decline of hemoglobin.For children responding poorly to hemostatic agents,interventional therapy is recommended.
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Memo
收稿日期:2023-10-9。
基金项目:国家自然科学基金重大项目(82293665)
通讯作者:阴捷,Email:yinjie1015@126.com