Zhang Li,Wang Junlu,Gu Zhiqing,et al.Application of accelerated rehabilitation surgical management plus erector spinal plane block during postoperative analgesia of children with tethered spinal cord[J].Journal of Clinical Pediatric Surgery,,22():1065-1071.[doi:10.3760/cma.j.cn101785-202304029-012]
Application of accelerated rehabilitation surgical management plus erector spinal plane block during postoperative analgesia of children with tethered spinal cord
- Keywords:
- Accelerated Rehabilitation Surgery; Erector Spinal Plane Block Anesthesia; Child; Tethered Cord; Analgesic Management
- Abstract:
- Objective To explore the clinical efficacy of enhanced recovery after surgery (ERAS) plus erector spinae plane block (ESPB) for post-untethering analgesia in children.Methods The relevant clinical data were retrospectively reviewed for 79 children with tethered cord syndrome (TCS) from January 2020 to November 2022.A total of 40 cases were in conventional administration group from January 2020 to March 2021 and 39 cases in ERAS+ESPB group from April 2021 to November 2022.Pain degrees,function outcomes and complication rates of two groups were compared within 3 days post-operation.Results Significant inter-group differences existed in pain scores at 24/48/72 h post-operation (F=24.261,P<0.001).Pain scores of conventional and ERAS+ESPB groups were statistically significant (F=176.080,P<0.001).Interaction between time factor and group was statistically significant (F=9.566,P<0.001).Further analysis of separate effects of postoperative analgesic management at different monitoring timepoints and groups revealed no statistically significant difference in pain scores between 24 h and 48 h post-operation in conventional group (P=0.180) and pain scores declined significantly at 72 h versus 24/48 h post-operation (P<0.001).Pain scores at Day 3 post-operation decreased obviously with the elapsing of time in ERAS+ESPB group (P<0.001).Pain scores were significantly lower in ERAS+ESPB group than those in conventional group at 24/48/72 h post-operation (P<0.001).Regarding postoperative function outcomes,length of hospital stay dropped in ERAS+ESPB group compared with conventional group [(9.23±1.13) vs.(13.85±2.9) day,t=4.683,P=0.022],frequency of postoperative analgesic pump compression declined greatly in ERAS+ESPB group versus conventional group[(5.67±1.94) vs.(9.18±2.65),t=3.818,P=0.031].Start time of postoperative functional exercise of lower extremity was significantly shorter in ERAS+ESPB group than that in conventional group [(4.62±0.66) vs.(7.75±0.54) day,t=8.689,P=0.006].No inter-group difference existed in catheter removal time [(6.66±0.84) vs.(6.51±0.72) day,t=1.665,P=0.249].The incidence of postoperative complications was significantly lower in ERAS+ESPB group than that in conventional group [n=3(7.7%) vs.n=10(25%),χ2=4.302,P=0.038].Conclusions Implementing ERAS plus ESPB can effectively control early postoperative pain,accelerate function recovery,reduce complications,shorten hospital stay and improve quality-of-life in TCS children.
References:
[1] Tu A,Steinbok P.Occult tethered cord syndrome:a review[J].Childs Nerv Syst,2013,29(9):1635-1640.DOI:10.1007/s00381-013-2129-1.
[2] Kobets AJ,Oliver J,Cohen A,et al.Split cord malformation and tethered cord syndrome:case series with long-term follow-up and literature review[J].Childs Nerv Syst,2021,37(4):1301-1306.DOI:10.1007/s00381-020-04978-9.
[3] Joliat GR,Labgaa I,Hübner M,et al.Cost-benefit analysis of the implementation of an enhanced recovery program in liver surgery[J].World J Surg,2016,40(10):2441-2450.DOI:10.1007/s00268-016-3582-2.
[4] Ni XF,Jia D,Guo YC,et al.The efficacy and safety of enhanced recovery after surgery (ERAS) program in laparoscopic digestive system surgery:a meta-analysis of randomized controlled trials[J].Int J Surg,2019,69:108-115.DOI:10.1016/j.ijsu.2019.07.034.
[5] 中华医学会外科学分会,中华医学会麻醉学分会.加速康复外科中国专家共识暨路径管理指南(2018)[J].中华麻醉学杂志,2018,38(1):8-13.DOI:10.3760∕cma.j.issn.0254-1416.2018.01.003. Branch of Surgery,Chinese Medical Association;Branch of Anesthesiology,Chinese Medical Association:Consensus on ERAS and Guidelines for Pathway Management in China (2018)[J].Chin J Anesthesiol,2018,38(1):8-13.DOI:10.3760/cma.j.issn.0254-1416.2018.01.003.
[6] Agarwal R,Rajanbabu A,Nitu PV 5th,et al.A prospective study evaluating the impact of implementing the ERAS protocol on patients undergoing surgery for advanced ovarian cancer[J].Int J Gynecol Cancer,2019,29(3):605-612.DOI:10.1136/ijgc-2018-000043.
[7] Kühlmann AYR,de Rooij A,Kroese LF,et al.Meta-analysis evaluating music interventions for anxiety and pain in surgery[J].Br J Surg,2018,105(7):773-783.DOI:10.1002/bjs.10853.
[8] Weiser TG,Haynes AB,Molina G,et al.Size and distribution of the global volume of surgery in 2012[J].Bull World Health Organ,2016,94(3):201-209F.DOI:10.2471/BLT.15.159293.
[9] 刘方,刘文,于腾旭.基于气质视角的情绪调节与儿童问题行为[J].心理科学进展,2019,27(4):646-656.DOI:10.3724/SP.J.1042.2019.00646. Liu F,Liu W,Yu TX.Emotion regulation and pediatric problem behaviors based upon the perspective of temperament[J].Adv Psychol Sci,2019,27(4):646-656.DOI:10.3724/SP.J.1042.2019.00646.
[10] 昝望,潘鑫,熊苗苗,等.术前高度焦虑相关致痛因子的变化及其对术后疼痛的影响[J].临床麻醉学杂志,2018,34(8):768-772.DOI:10.12089/jca.2018.08.009. Zan W,Pan X,Xiong MM,et al.Changes in severe preoperative anxiety related pain factors and their effect on postoperative pain[J].J Clin Anesthesiol,2018,34(8):768-772.DOI:10.12089/jca.2018.08.009.
[11] 陈园,谢鑑辉.基于格林模式儿童哮喘控制水平影响因素问卷的编制[J].中国医药科学,2022,12(8):16-20.DOI:10.3969/j.issn.2095-0616.2022.08.006. Chen Y,Xie JH.Preparation of a questionnaire on factors influencing the control level of childhood asthma based upon the precede-proceed model[J].China Med Pharm,2022,12(8):16-20.DOI:10.3969/j.issn.2095-0616.2022.08.006.
[12] 刘俊杰,赵俊.现代麻醉学[M].北京:人民卫生出版社,1997:838-846. Liu JJ,Zhao J.Modern Anesthesiology[M].Beijing:People’s Medical Publishing House,1997:838-846.
[13] Jellish WS,Leonetti JP,Buoy CM,et al.Facial nerve electromyographic monitoring to predict movement in patients titrated to a standard anesthetic depth[J].Anesth Analg,2009,109(2):551-558.DOI:10.1213/ane.0b013e3181ac0e18.
[14] DeinerS.Highlights of anesthetic considerations for intraoperative neuromonitoring[J].Semin Cardiothorac Vasc Anesth,2010,14(1):51-53.DOI:10.1177/1089253210362792.
[15] Sloan TB.Muscle relaxant use during intraoperative neurophysiologic monitoring[J].J Clin Monit Comput,2013,27(1):35-46.DOI:10.1007/s10877-012-9399-0.
[16] Rozet I,Metzner J,Brown M,et al.Dexmedetomidine does not affect evoked potentials during spine surgery[J].Anesth Analg,2015,121(2):492-501.DOI:10.1213/ANE.0000000000000840.
[17] Sloan TB,Vasquez J,Burger E.Methohexital in total intravenous anesthesia during intraoperative neurophysiological monitoring[J].J Clin Monit Comput,2013,27(6):697-702.DOI:10.1007/s10877-013-9490-1.
[18] 熊巍,王增春,张军卫,等.全麻下脊柱脊髓手术中神经电生理监测异常的原因分析[J].中国康复理论与实践,2017,23(4):424-429.DOI:10.3969/j.issn.1006-9771.2017.04.013. Xiong W,Wang ZC,Zhang JW,et al.Analysis of abnormalities of intraoperative neurophysiological monitoring during spine and spinal cord surgery under general anesthesia[J].Chin J Rehabil Theory Pract,2017,23(4):424-429.DOI:10.3969/j.issn.1006-9771.2017.04.013.
[19] KohtA,Sloan TB,Toleikis JR.围术期神经系统监测[M].韩如泉,乔慧,译.北京:北京大学医学出版社,2013:74-78. Koht A,Sloan TB,Toleikis JR.Monitoring the nervous system for anesthesiologists and other health care professionals[M].Translated by Han RQ,Qiao H,Beijing:Peking University Medical Press,2013:74-78.
[20] 于琳琳,王军,马越,等.不同肌松水平对术中脊髓神经电生理监测的影响[J].首都医科大学学报,2017,38(3):357-360.DOI:10.3969/j.issn.1006-7795.2017.03.006. Yu LL,Wang J,Ma Y,et al.Influence of different neuromuscular blockade levels on intraoperative spinal cord monitoring[J].J Capit Med Univ,2017,38(3):357-360.DOI:10.3969/j.issn.1006-7795.2017.03.006.
[21] 余奇劲,郭咸希.罗哌卡因竖脊肌神经阻滞辅助全身麻醉用于腰椎手术30例[J].医药导报,2018,37(1):63-66.DOI:10.3870/j.issn.1004-0781.2018.01.016. Yu QJ,Guo XX.Ropivacaine erector spinae plane block assisting general anesthesia during lumbar spine surgery:a report of 30 cases[J].Herald Med,2018,37(1):63-66.DOI:10.3870/j.issn.1004-0781.2018.01.016.
[22] 粟佳佳,李琪英.超声引导区域神经阻滞在腰椎手术麻醉中的应用[J].河北医科大学学报,2021,42(5):617-620.DOI:10.3969/j.issn.1007-3205.2021.05.025. Su JJ,Li QY.Application of ultrasound-guided regional nerve block during lumbar surgery anesthesia[J].J Hebei Med Univ,2021,42(5):617-620.DOI:10.3969/j.issn.1007-3205.2021.05.025.
[23] Hockenberry MJ,Wilson D.Wong’s Essentials of Pediatric Nursing[M].8th ed.St.Louis:Mosby,2008:l-1280.
[24] 洪彩霞,钱虹,黄群,等.两种测定方法评定儿童牙齿疼痛的效果比较[J].广东医学,2014,35(13):2077-2078.DOI:10.13820/j.cnki.gdyx.2014.13.039. Hong CX,Qian H,Huang Q,et al.Comparison of two methods in the assessment of dental pain in children[J].Guangdong MedJ,2014,35(13):2077-2078.DOI:10.13820/j.cnki.gdyx.2014.13.039.
[25] Vincent HK,Horodyski MB,Vincent KR,et al.Psychological distress after orthopedic trauma:prevalence in patients and implications for rehabilitation[J].PM R,2015,7(9):978-989.DOI:10.1016/j.pmrj.2015.03.007.
[26] 惠丰荷.预见性护理在骨科护理中的应用思路[J].中国医药指南,2014,12(32):345-346.DOI:10.15912/j.cnki.gocm.2014.32.268. Hui FH.Application of predictive nursing in orthopedics nursing[J].Guide China Med,2014,12(32):345-346.DOI:10.15912/j.cnki.gocm.2014.32.268.
[27] 唐小红,陈秋萍,罗善珍,等.加速康复外科理念在骨科患者围手术期护理的效果观察[J].中国实用医药,2020,15(31):194-196.DOI:10.14163/j.cnki.11-5547/r.2020.31.085. Tang XH,Chen QP,Luo SZ,et al.Observation of effect of accelerated rehabilitation surgery concept in perioperative nursing of orthopaedic patients[J].China Pract Med,2020,15(31):194-196.DOI:10.14163/j.cnki.11-5547/r.2020.31.085.
[28] 方国英.护理干预对改善硬膜外麻醉手术患者术后疼痛及减少并发症发生的作用[J].世界最新医学信息文摘,2019,19(78):314-315.DOI:10.19613/j.cnki.1671-3141.2019.78.210. Fang GY.Effect of nursing intervention on improving postoperative pain and reducing complications in patients undergoing epidural anesthesia[J].World Latest Med Inf,2019,19(78):314-315.DOI:10.19613/j.cnki.1671-3141.2019.78.210.
[29] 周小敏,周林荣,龚兰娟,等.基于ERAS理念的多模式镇痛护理管理对肺叶切除术后病人疼痛控制的影响[J].全科护理,2022,20(28):3971-3974.DOI:10.12104/j.issn.1674-4748.2022.28.022. Zhou XM,Zhou LR,Gong LJ,et al.Effects of multi-modal analgesic nursing management based upon ERAS concept on pain control in patients after pulmonary lobectomy[J].Chin Gen Pract Nurs,2022,20(28):3971-3974.DOI:10.12104/j.issn.1674-4748.2022.28.022.
[30] 乔丽艳,郝占元,左灵.加速康复外科理念下麻醉管理在腰椎手术中的应用[J].中国医药导报,2021,18(4):107-110,138. Qiao LY,Hao ZY,Zuo L.Application of anesthesia management during lumbar spine surgery under the concept of enhanced recovery after surgery[J].China Med Herald,2021,18(4):107-110,138.
[31] 田爱现,马剑雄,马信龙,等.加速康复外科理念在脊柱骨折围手术期中的应用研究[J].中国中西医结合外科杂志,2021,27(5):729-733.DOI:10.3969/j.issn.1007-6948.2021.05.011. Tian AX,Ma JX,Ma XL,et al.Application of enhanced recovery after surgery (ERAS) in perioperative treatment of spinal fracture[J].Chin J Integr Surg,2021,27(5):729-733.DOI:10.3969/j.issn.1007-6948.2021.05.011.
[32] 苏怀轩,江伟航,黄政通,等.加速康复外科理念在宫颈癌手术麻醉管理中的应用效果[J].实用临床医学,2018,19(8):41-43.DOI:10.13764/j.cnki.lcsy.2018.08.013. Su HX,Jiang WH,Huang ZT,et al.Application of enhanced recovery after surgery during anesthetic management for cervical cancer surgery[J].Pract Clin Med,2018,19(8):41-43.DOI:10.13764/j.cnki.lcsy.2018.08.013.
[33] 胡梦珑,戚继荣.围手术期加速康复理念在漏斗胸中的应用进展[J].临床小儿外科杂志,2022,21(6):582-585.DOI:10.3760/cma.j.cn101785-202002009-016. Hu ML,Qi JR.Research advances in enhanced recovery after surgery for pediatric pectus excavatum during perioperative period[J].J Clin Ped Sur,2022,21(6):582-585.DOI:10.3760/cma.j.cn101785-202002009-016.
[34] Shida D,Tagawa K,Inada K,et al.Enhanced recovery after surgery (ERAS) protocols for colorectal cancer in Japan[J].BMC Surg,2015,15:90.DOI:10.1186/s12893-015-0079-0.
Memo
收稿日期:2023-4-11。
基金项目:上海市科学技术委员会上海市2020年度科技创新行动计划医学创新研究专项项目(20Y11905800)
通讯作者:王君璐,Email:wangjunlu_@126.com