Wang Hongqin,Huang Min,Hu Binya,et al.Clinical features and operative efficacies of juvenile onset laryngeal papilloma[J].Journal of Clinical Pediatric Surgery,,22():966-970.[doi:10.3760/cma.j.cn101785-202301017-012]
Clinical features and operative efficacies of juvenile onset laryngeal papilloma
- Keywords:
- Larynx; Papilloma; Physiopathology; Surgical Procedures; Operative; Treatment Outcome; Child
- Abstract:
- Objective To explore the clinical features,surgical approaches and curative efficacies of children with juvenile onset laryngeal papilloma over the last decade.Methods From January 2013 to October 2022,63 children hospitalized with laryngeal papilloma at Hunan Children’s Hospital were recruited as research subjects.The relevant clinical data were retrospectively reviewed,including general profiles,initial presentations and the results of electronic fiber laryngoscopy.The outcomes were recorded for 55 children initially operated.Results The median average age of onset was 25 months.Fifty-three cases (n=53,84.1%) had no obvious cause of clinical symptoms.The initial symptom of 63 cases (100%) was hoarseness associated with dyspnea (n=11,17.5%),throat ringing (n=14,22.2%) and shortness of breath (n=6,9.5%).The postoperative pathological diagnosis was laryngeal squamous epithelial papilloma.seventeen cases (n=17,27.0%) underwent immunohistochemical examination and 7 cases (n=7,11.1%) were infected with human papilloma virus.All lesions of laryngeal papilloma were removed under general anesthesia with laryngoscopic assistance.Removal was completed by cold instruments (n=53,96.4%) and electric suction and cold instruments (n=2,3.6%).Interventions included 0.1% adrenaline for hemostasis (n=22,40.0%),electroscalpel for hemostasis (n=31,56.4%) and bipolar electrocoagulation (n=2,3.6%).There were vocal cord scar (n=1,1.8%),vocal cord adhesion (n=4,7.3%) and laryngeal stenosis (n=2,3.6%).Postoperative recurrence occurred in 37 cases (37/55,67.3%).Conclusion Age of initial occurrence of laryngeal papilloma is usually 1-3 years.The presenting symptom is hoarseness associated with throat ringing and dyspnea.Common postoperative complications include vocal cord scar,vocal cord adhesion and laryngeal stenosis.As compared with previous reports,cold instrument resection of papilloma has a higher recurrence rate with fewer postoperative complications.
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Memo
收稿日期:2023-1-29。
通讯作者:赵斯君,Email:zhaosj3991@sohoo.com