Sun Jie,Sun Ning,Zhang Weiping,et al.Role of distal ureteral diameter ratio in predicting early breakthrough urinary tract infections in children with primary vesicoureteral reflux[J].Journal of Clinical Pediatric Surgery,,22():917-923.[doi:10.3760/cma.j.cn101785-202305019-004]
Role of distal ureteral diameter ratio in predicting early breakthrough urinary tract infections in children with primary vesicoureteral reflux
- Keywords:
- Vesico-Ureteral Reflux; Distal Ureteral Diameter Ratio; Forecasting; Urinary Tract Infection; Child
- Abstract:
- Objective To evaluate the application value of distal ureter diameter ratio as a predictive factor for breakthrough urinary tract infection (BT-UTI) in children with primary vesicoureteral reflux (VUR).Methods From January 2018 to December 2020,retrospective review was performed for the clinical features of 102 VUR children.Clinical data were collected for identifying the predictors of BT-UTI.Demographics,VUR grade,laterality,distal ureter diameter and UDR were examined by univariate and multivariable analyses.Primary outcome was BT-UTI.Results Among them,31 children (30.3%) experienced BT-UTI events.Based upon multivariate analysis,gender,maximal grade of reflux and laterality were not the predictors of BT-UTI.Ureteral diameter ratio (UDR)(P=0.0417,OR=11.4,95%CI:1.259-141.919) and age (P=0.0467,OR=0.975,95%CI:0.949-0.997) were among the strongest predictors of early febrile BT-UTI in VUR children.Conclusion Children with elevated distal UDR are at an elevated risk for BT-UTI independent of reflux grade.As an objective measurement of VUR,UDR provides valuable prognostic information for risks of recurrent pyelonephritis and may assist with clinical decision-making.
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Memo
收稿日期:2023-5-12。
通讯作者:孙宁,Email:drsunningbch@sina.com