Wang Denghui,Cui Mengjie,Han Xiaojiang,et al.Risk factors of complications after urethroplasty in children with gender dysplasia and proximal hypospadias[J].Journal of Clinical Pediatric Surgery,,22():849-854.[doi:10.3760/cma.j.cn101785-202211056-010]
Risk factors of complications after urethroplasty in children with gender dysplasia and proximal hypospadias
- Keywords:
- Disorders of Sex Development; Hypospadias; Surgical Procedures; Operative; Child
- Abstract:
- Objective To explore the risk factors of complications after urethroplasty in children with DSD (disorders of sex development) plus proximal hypospadias.Methods From January 2012 to January 2020,clinical data were retrospectively reviewed for 40 DSD children with concurrent proximal hypospadias admitted with a follow-up period of no less than 2 years.Age of an initial admission,type of DSD,preoperative comorbidities,surgical approaches of urethroplasty,length of urethroplasty,external masculinization score (EMS),preoperative use of hormone therapy and recent postoperative complications were recorded.The influencing factors of recent postoperative complications in DSD children with concurrent proximal hypospadias.Results The average age was 44(13-128) month.A total of 10 cases (10/40,25%) of complications occurred,including urinary fistula (n=7),urethral stricture (n=1),urethral rupture (n=1) and postoperative reflux epididymitis(n=1).There was a statistically significant difference (P<0.05) in preoperative hormone therapy[(2/10)vs.(19/30)], EMS score[5.5(4,8)vs. 8(7,8)], and the presence of small penises[(6/10)vs.(5/30)] between the complication group and the non complication group, while there was no statistically significant difference (P>0.05) in admission age[39.0(18.75,58.50)vs. 30.5(22.00,38.75)], DSD type[(3/10)vs.(4/10)vs.(3/10)], and urethroplasty length[Primary 5.0(5.0,6.0)vs.3.0(2.0,4.0),Staged 4.5(4.25,8.75)vs. 5.0(4.5,6.5)] between the two groups. Conclusion For DSD children with concurrent proximal hypospadias,preoperative hormone therapy,EMS and presence of a small penis are risk factors for the occurrence of short-term postoperative complications.
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Memo
收稿日期:2022-11-29。
基金项目:河南省联合重点基金项目(SBGJ202002042)
通讯作者:范应中,Email:fanyingzhong2@163.com