Long Junshan,Zhang Jing,Su Xiaoxia,et al.Research advances of targeted therapy for neuroblastoma in children[J].Journal of Clinical Pediatric Surgery,,22():619-624.[doi:10.3760/cma.j.cn101785-202303039-004]
Research advances of targeted therapy for neuroblastoma in children
- Keywords:
- Neuroblastoma; Molecular Targeted Therapy; Surgical Procedures; Operative; Child
- Abstract:
- Neuroblastoma (NB) is a malignant solid tumor typically originating from sympathetic nervous system cells in children.Although traditional interventions of chemotherapy, surgery and radiotherapy may arrest the progression of NB, they often fail to obtain a complete cure.Recently targeted therapy has emerged as a novel therapeutic option for NB.Drugs or other means are employed for selectively acting upon certain molecules in tumor cells, thus inhibiting their growth and metastasis.This review summarized the latest researches of targeted therapy for NB, such as antibodies targeting NB-specific expression and targeted drugs for NB-related signaling pathways.
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Memo
收稿日期:2023-03-13。
基金项目:海南省临床医学中心建设项目(QWYH202175)
通讯作者:董琦,Email:dqearth@163.com