Chen Xinyuan,Li Zhi.Updates in diagnosis and treatment of inflammatory myofibroblastic tumor in children[J].Journal of Clinical Pediatric Surgery,,22():296-300.[doi:10.3760/cma.j.cn101785-202204073-018]
Updates in diagnosis and treatment of inflammatory myofibroblastic tumor in children
- Keywords:
- Inflammatory Myofibroblastic Tumor; Inflammatory Pseudotumor; Target Therapy; ALK Inhibitors
- Abstract:
- Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor in children.Clinical manifestations of IMTs are associated with mass tumor effect and local inflammatory responses and differ according to tumor location.Surgical resection is an optimal treatment option with a high recurrence rate.IMT remains insensitive to chemoradiotherapy.With rapid developments of next-generation sequencing and targeted drug dosing,clinicians have acquired a deeper understanding of its histological characteristics and biological behaviors.Managements and evaluation strategies for this disease have greatly changed.Etiologies,clinical characteristics and treatments of IMT were summarized for optimal managements of IMT in children.
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Memo
收稿日期:2022-4-24。
基金项目:国家自然科学基金(81400579)
通讯作者:李智,Email:lizhimdphd@163.com