Hou Longlong,Lin Tulian,He Qiuming,et al.Prenatal identification of hernia sac in congenital diaphragmatic hernia and its effect on prognosis[J].Journal of Clinical Pediatric Surgery,,21():827-832.[doi:10.3760/cma.j.cn101785-202206003-006]
Prenatal identification of hernia sac in congenital diaphragmatic hernia and its effect on prognosis
- Keywords:
- Hernias; Diaphragmatic; Congenital/CO; Prenatal Diagnosis/MT; Infant; Newborn; Prognosis
- Abstract:
- Objective To evaluate the accuracy identification of hernia sac in congenital diaphragmatic hernia (CDH) by fetal magnetic resonance and examine the prognostic effect of hernia sac on CDH.Methods From January 1, 2013 to December 31, 2020, 62 CDH neonates receiving fetal magnetic resonance (MR) and undergoing surgical intervention were selected as subjects.According to the presence or absence of hernia sac, they were divided into two groups of hernia sac (n=26) and non-hernia sac (n=36).Prenatal profiles, intrapartum status, clinical features and outcomes of CDH were compared between two groups.Results Hernia sac was detected in 18 infants during fetal period and the detection rate of fetal MR for hernia sac was 69.2%.No significant inter-group differences existed in o/e TFLV, gender, gestational age, birth weight, 1/5-min Apgar score, surgical approach, patch usage, defect size, days of ventilation, hospital stay or utilization rate (P>0.05).The hernia sac group had a higher PPLV (P < 0.05).As compared with non-hernia sac group, there were more right-side CDH children and more cases of liver herniation in hernia sac group (P < 0.05).The survival rate was 100% in hernia sac group and 86.1% in non-hernia sac group and the difference was statistically significant (P < 0.05).Conclusion MR can well identify the presence of a hernia sac in CDH during prenatal period.Hernia sac group has better prenatal assessment parameters with a higher postnatal survival.
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Memo
收稿日期:2022-06-02。
基金项目:广东省自然科学基金（2020A1515010296）
通讯作者:钟微,E-mail:zhongwei@gwcmc.org