He Min,Cai Jiabin,Mao Junqin,et al.Surgical treatment for stage Ⅰ testicular malignant germ cell tumors via scrotal incision[J].Journal of Clinical Pediatric Surgery,,21():643-647.[doi:10.3760/cma.j.cn101785-202008007-009]
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Surgical treatment for stage Ⅰ testicular malignant germ cell tumors via scrotal incision

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: 第21卷 Number: 2022 07 Page: 643-647 Column: 论著 Date of publication: 2022-07-28
Author(s):
He Min1;  Cai Jiabin1;  Mao Junqin1;  Li Minju1;  Tang Daxing2;  Shu Qiang1;  Wang Jinhu1
1 Department of Surgical Oncology, The Children’s Hospital, Zhejiang University School Of Medicine, National Clinical Research Center For Child Health, Hangzhou, 310000, China;
2 Department of Urological Surgery, The Children’s Hospital, Zhejiang University School Of Medicine, National Clinical Research Center For Child Health, Hangzhou, 310000, China
Keywords:
Germinoma; Testicular Neoplasms; Scrotum/SU; Groin/SU
DOI:
10.3760/cma.j.cn101785-202008007-009
Abstract:
Objective To explore the safety and feasibility of surgery for stage Ⅰ testicular malignant germ cell tumors via scrotal incision.Methods From January 2014 to December 2019, clinical data were retrospectively reviewed for 41 children with testicular malignant germ cell tumor without inguinal or retroperitoneal lymph node enlargement.The median age was 36(4-96) months.According to operative approach, they were divided into scrotal and inguinal groups.Perioperative related parameters and postoperative complications were compared between two groups.Results Both groups completed operations smoothly.No significant inter-group differences existed in age, body weight, tumor diameter or pathological type (P>0.05).Operative duration and postoperative hospitalization time of scrotal group were (39.3±9.2) min and (3.6±1.5) d respectively and that of groin group was (42.0±8.6) min and (4.3±2.2) d and the inter-group difference was not statistically significant (P>0.05).In scrotal group, preoperative value of alpha fetoprotein (AFP) was (7 203.9±16 096.3) ng/mL, (21.2±14.0) ng/mL at Month 1 post-operation and (12.9±9.4) ng/mL at Month 2 post-operation.In inguinal group, AFP value was (5 048.8±8 106.1) ng/mL pre-operation, (32.2±41.3) ng/mL at Month 1 post-operation and (22.4±37.9) ng/mL at Month 2 post-operation.After operation, AFP in both groups was significantly lower than that pre-operation with statistical significance (P<0.05).No significant inter-group difference existed in AFP value (P>0.05).In terms of complications, one case of incision dehiscence occurred in scrotal group while no perioperative complication was observed in inguinal group.The postoperative follow-up period of two groups was (6-74)(8-69) months.The overall survival rate was 100% and the event-free survival rate 13/14 and 24/27 without statistical significance (P>0.05).Conclusion Surgery via scrotal incision for stage Ⅰ testicular malignant germ cell tumors can achieve the same efficacy and prognosis as traditional inguinal incision.The operation is simple and the complications are controllable.Wider popularization is worthwhile.

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Memo

收稿日期:2020-08-03。
基金项目:浙江省自然科学基金（LQ20H160027）
通讯作者:王金湖,Email:wjh@zju.edu.cn

Last Update: 1900-01-01