Zhang Yi,Ma Lishuang,Cao Ling,et al.Clinical observation of recent postoperative pulmonary function in patients with congenital phrenic hernia[J].Journal of Clinical Pediatric Surgery,,21():236-241.[doi:10.3760/cma.j.cn101785-202107030-007]
Clinical observation of recent postoperative pulmonary function in patients with congenital phrenic hernia
- Keywords:
- Hernias; Diaphragmatic; Congenital/SU; Treatment Outcome; Respiratory Function Tests; Observational Studies as Topic
- Abstract:
- Objective To analyze the recent postoperative lung function of children with congenital diaphragmatic hernia (CDH), and explore the risk factors affecting lung function to guide the clinical follow-up.Methods The clinical data of children undergoing CDH repair and lung function examination from April 2016 to January 2021 was retrospectively reviewed.According to the result of lung function exmination, they were divided into normal group and abnormal group (including obstructive ventilation dysfunction, restricted ventilation dysfunction and mixed ventilation dysfunction) and compared the intergroup differences.The mean time of lung function test was 1.6 months (11 days-18 months) after repair.Results Of the 32 cases of CDH children.5 (15.6%) had normal pulmonary functionwhile other 27(84.4%) had adnormal pulmonary function.Subject to the result of the first lung function examination, 20(62.5%) cases showed obstructive ventilation dysfunction, 3(9.4%) cases showed restricted ventilation dysfunction, and 4(12.5%) cases showed mixed ventilation dysfunction.Both normal and abnormal groups had statistical differences in pulmonary artery hypertension(2/5 vs.23/27, P<0.05), oxygen duration[(12.22±6.09) d vs.(21.48±9.12) d, P<0.05].The oxygen use at 30 days after birth had no significant statistical significance.The mean of prenatal diagnosis time of abnormal group was significantly smaller than normal group, but there was no significant statistical difference[(30.67±3.51) w vs.(26.77±4.38) w, P>0.05].Conclusion Attention should be paid to CDH children who have different degrees of lung dysfunction early after surgery.Obstructive ventilation dysfunction is more common after CDH repair.Arterial hypertension and oxygen use duration may be risk factors for lung dysfunction.It is speculated that the prenatal diagnosis time may affect the lung function of children with CDH.
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Memo
收稿日期:2021-07-16。
基金项目:国家重点研发计划（2018YFC1002503）；北京市卫生与健康科技成果与适宜技术推广项目（BHTPP202005）；北京市儿科学科协同发展中心儿科重点专项（XTZD20180305）
通讯作者:马立霜,Email:malishuang2006@sina.com