Zhan Yong,Zheng Shan.Research advances of epigenetics in biliary atresia[J].Journal of Clinical Pediatric Surgery,,20():1070-1075.[doi:10.12260/lcxewkzz.2021.11.014]
Research advances of epigenetics in biliary atresia
- Keywords:
- Biliary Atresia; Epigenetic Research
- CLC:
- R722;R394.3;R575
- Abstract:
- Epigenetics is the study on regulating process and mechanism of gene expression without alterations in DNA sequence. Recent researches have shown that epigenetics plays an important role in the development of biliary atresia through complex regulating mechanisms, which contributes to the diagnosis, prognosis evaluation and treatment of biliary atresia. This review summarized the latest epigenetics research in biliary atresia.
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Memo
收稿日期:2020-07-24。
基金项目:国家自然基金面上项目(编号:81974059);上海申康医院发展中心临床三年行动计划疑难疾病精准诊治攻关项目(编号:SHDC2020CR2009A);2017年上海市重中之重临床重点学科建设项目(编号:2017ZZ02022)
通讯作者:郑珊,Email:szheng@shmu.edu.cn