Yao Mengnan,Zhang Jianmin,Sun Lan,et al.Study of median effective volume of 0.2% ropivacaine for ultrasound-guided brachial plexus block in children[J].Journal of Clinical Pediatric Surgery,,20():951-955.[doi:10.12260/lcxewkzz.2021.10.011]
Study of median effective volume of 0.2% ropivacaine for ultrasound-guided brachial plexus block in children
- CLC:
- R614;R614.4;R971.2
- Abstract:
- Objective To determine the median effective volume (EV50) of 0.2% ropivacaine for ultrasound-guided brachial plexus block (BPB) in children.Methods Twenty-six preschool children, 14 males and 12 females, American Society of Anesthesiologists physical status Ⅰ~Ⅱ, weighing 10.1-28.4 kg, scheduled for humeral supracondylar fractures surgery sequentially received an ultrasound-guided BPB with 0.2% ropivacaine.The modified Dixon’s up-and-down method was adopted in the test with the initial dose 1 mL/kg.Based on the outcome of the preceding block, a positive or negative block resulted in a 0.1 mL/kg reduction or increase in volume, respectively.The EV50 and 95% confidence interval (95%CI) of 0.2% ropivacaine were calculated by Probit Regression method.Results In the ultrasound-guided brachial plexus block in preschoolers with humeral supracondylar fractures surgery, the EV50 and 95%CI of 0.2% ropivacaine was 0.298 mL/kg and 0.188-0.727 mL/kg.Conclusion The EV50 of 0.2% ropivacaine for an ultrasound-guided brachial plexus block in preschool children with humeral supracondylar fractures surgery was 0.298 mL/kg.
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Memo
收稿日期:2021-01-01。
通讯作者:张建敏,Email:zjm428@sina.com