Yang Sha,Zhai Xuan.Recent advances in the treatment of brain injury in premature infants[J].Journal of Clinical Pediatric Surgery,,20():876-880.[doi:10.12260/lcxewkzz.2021.09.015]
Click Copy

Recent advances in the treatment of brain injury in premature infants

References:

1 Mwaniki MK,Atieno M,Lawn JE,et al.Long-term neurodevelopmental outcomes after intrauterine and neonatal insults:a systematic review[J].Lancet,2012,379(9814):445-452.DOI:10.1016/S0140-6736(11)61577-8.
2 Yan F,Zhang M,Meng Y,et al.Erythropoietin improves hypoxic-ischemic encephalopathy in neonatal rats after short-term anoxia by enhancing angiogenesis[J].Brain Res,2016,1651:104-113.DOI:10.1016/j.brainres.2016.09.024.
3 Larpthaveesarp A,Ferriero DM,Gonzalez FF.Growth factors for the treatment of ischemic brain injury (growth factor treatment)[J].Brain Sci,2015,5(2):165-177.DOI:10.3390/brainsci5020165.
4 Wei S,Luo C,Yu S,et al.Erythropoietin ameliorates early brain injury after subarachnoid haemorrhage by modulating microglia polarization via the EPOR/JAK2-STAT3 pathway[J].Exp Cell Res,2017,361(2):342-352.DOI:10.1016/j.yexcr.2017.11.002.
5 Wu H,Zhao J,Chen M,et al.The anti-aging effect of erythropoietin via the erk/nrf2-are pathway in aging rats[J].J Mol Neurosci,2017,61(3):449-458.DOI:10.1007/s12031-017-0885-1.
6 Wu YW,Bauer LA,Ballard RA,et al.Erythropoietin for neuroprotection in neonatal encephalopathy:safety and pharmacokinetics[J].Pediatrics,2012,130(4):683-691.DOI:10.1542/peds.2012-0498.
7 Fauchere JC,Dame C,Vonthein R,et al.An approach to using recombinant erythropoietin for neuroprotection in very preterm infants[J].Pediatrics,2008,122(2):375-382.DOI:10.1542/peds.2007-2591.
8 Song J,Sun H,Xu F,et al.Recombinant human erythropoietin improves neurological outcomes in very preterm infants[J].Ann Neurol,2016,80(1):24-34.DOI:10.1002/ana.24677.
9 Natalucci G,Latal B,Koller B,et al.Effect of early prophylactic high-dose recombinant human erythropoietin in very preterm infants on neurodevelopmental outcome at 2 years:a randomized clinical trial[J].JAMA,2016,315(19):2079-2085.DOI:10.1001/jama.2016.5504.
10 Juul SE,Comstock BA,Wadhawan R,et al.A randomized trial of erythropoietin for neuroprotection in preterm infants[J].N Engl J Med,2020,382(3):233-243.DOI:10.1056/NEJMoa1907423.
11 Kellert BA,Mcpherson RJ,Juul SE.A comparison of high-dose recombinant erythropoietin treatment regimens in brain-injured neonatal rats[J].Pediatr Res,2007,61(4):451-455.DOI:10.1203/pdr.0b013e3180332cec.
12 Gonzalez FF,Larpthaveesarp A,Mcquillen P,et al.Erythropoietin increases neurogenesis and oligodendrogliosis of subventricular zone precursor cells after neonatal stroke[J].Stroke,2013,44(3):753-758.DOI:10.1161/stroke-aha.111.000104.
13 Ohls RK,Christensen RD,Widness JA,et al.Erythropoiesis stimulating agents demonstrate safety and show promise as neuroprotective agents in neonates[J].J Pediatr,2015,167(1):10-12.DOI:10.1016/j.jpeds.2015.03.054.
14 Kandasamy Y,Kumar P,Hartley L.The effect of erythropoietin on the severity of retinopathy of prematurity[J].Eye (Lond),2014,28(7):814-818.DOI:10.1038/eye.2014.95.
15 Shiou SR,Yu Y,Chen S,et al.Erythropoietin protects intestinal epithelial barrier function and lowers the incidence of experimental neonatal necrotizing enterocolitis[J].J Biol Chem,2011,286(14):12123-12132.DOI:10.1074/jbc.M110.154625.
16 Davies A,Wassink G,Bennet L,et al.Can we further optimize therapeutic hypothermia for hypoxic-ischemic encephalopathy?[J].Neural Regen Res,2019,14(10):1678-1683.DOI:10.4103/1673-5374.257512.
17 Wu YW,Mathur AM,Chang T,et al.High-dose erythropoietin and hypothermia for hypoxic-ischemic encephalopathy:a phase ii trial[J].Pediatrics,2016,137(6):e20160191.DOI:10.1542/peds.2016-0191.
18 Yust-Katz S,Fisher-Shoval Y,Barhum Y,et al.Placental mesenchymal stromal cells induced into neurotrophic factor-producing cells protect neuronal cells from hypoxia and oxidative stress[J].Cytotherapy,2012,14(1):45-55.DOI:10.3109/14653249.2011.613928.
19 Donega V,Nijboer CH,Van Tilborg G,et al.Intranasally administered mesenchymal stem cells promote a regenerative niche for repair of neonatal ischemic brain injury[J].Exp Neurol,2014,261:53-64.DOI:10.1016/j.expneurol.2014.06.009.
20 Berger R,S?der S.Neuroprotection in preterm infants[J].Biomed Res Int,2015,2015:257139.DOI:10.1155/2015/257139.
21 Rosell A,Morancho A,Navarro-Sobrino M,et al.Factors secreted by endothelial progenitor cells enhance neurorepair responses after cerebral ischemia in mice[J].PLoS ONE,2013,8(9):e73244.DOI:10.1371/journal.pone.0073244.
22 Phillips AW,Johnston MV,Fatemi A.The potential for cell-based therapy in perinatal brain injuries[J].Transl Stroke Res,2013,4(2):137-148.DOI:10.1007/s12975-013-0254-5.
23 Yoshimoto M,Koenig JM.Stem cells:potential therapy for neonatal injury?[J].Clin Perinatol,2015,42(3):597-612.DOI:10.1016/j.clp.2015.04.008.
24 Amable PR,Teixeira MV,Carias RB,et al.Protein synthesis and secretion in human mesenchymal cells derived from bone marrow,adipose tissue and Wharton’s jelly[J].Stem Cell Res Ther,2014,5(2):53-65.DOI:10.1186/scrt442.
25 Vinukonda G,Liao Y,Hu F,et al.Human cord blood-derived unrestricted somatic stem cell infusion improves neurobehavioral outcome in a rabbit model of intraventricular hemorrhage[J].Stem Cells Transl Med,2019,8(11):1157-1169.DOI:10.1002/sctm.19-0082.
26 Fang B,Wang H,Sun XJ,et al.Intrathecal transplantation of bone marrow stromal cells attenuates blood-spinal cord barrier disruption induced by spinal cord ischemia-reperfusion injury in rabbits[J].J Vasc Surg, 2013,58(4):1043-1052.DOI:10.1016/j.jvs.2012.11.087.
27 McDonald CA,Djuliannisaa Z,Petraki M,et al.Intranasal delivery of mesenchymal stromal cells protects against neonatal hypoxic-ischemic brain injury[J].Int J Mol Sci,2019,20(10):2449.DOI:10.3390/ijms20102449.
28 Ahn SY,Chang YS,Sung DK,et al.Optimal route for mesenchymal stem cells transplantation after severe intraventricular hemorrhage in newborn rats[J].PLoS One,2015,10(7):e0132919.DOI:10.1371/journal.pone.0132919.
29 Ahn SY,Chang YS,Park WS.Stem cells for neonatal brain disorders[J]. Neonatology,2016,109(4):377-383.DOI:10.1159/000444905.
30 van Velthoven CT,Kavelaars A,van Bel F,et al.Mesenchymal stem cell transplantation changes the gene expression profile of the neonatal ischemic brain[J].Brain Behav Immun, 2011,25(7):1342-1348.DOI:10.1016/j.bbi.2011.03.021.
31 Tamura G,Inagaki T.Removal of a minimal amount of subdural hematoma is effective and sufficient for term neonates with severe symptomatic spontaneous parenchymal hemorrhage[J].Childs Nerv Syst,2019,35(11):2237-2240.DOI:10.1007/s00381-019-04114-2.

Memo

收稿日期:2020-04-05。
基金项目:重庆市科委基础科学与前沿技术研究重点项目(编号:cstc2015jcyjBX0144)
通讯作者:翟瑄,zhaixuan@163.com

Last Update: 1900-01-01