Lin Tulian,Lü Junjian,He Qiuming,et al.Association of fetal diaphragmatic hernia severity with prenatal indicators[J].Journal of Clinical Pediatric Surgery,,20():832-836.[doi:10.12260/lcxewkzz.2021.09.006]
Association of fetal diaphragmatic hernia severity with prenatal indicators
- Keywords:
- Fetus; Hernias; Diaphragmatic; Congenital/DI; Ultrasonography; Prenatal; Prenatal Diagnosis; Prognosis
- CLC:
- R655.6;R714.5
- Abstract:
- Objective To summarize the prenatal evaluation and prognosis of different grades of fetal diaphragmatic hernia.Methods A total of 62 CDH children admitted from January 1, 2017 to March 31, 2020 were recruited.According to the findings of fetal ultrasonography and magnetic resonance imaging (MRI), they were divided into mild CDH and moderate-severe CDH groups.The gestational age at birth, birth weight, diagnostic gestational age, o/e LHR, o/e TFLV, PPLV, liver hernia, hernia sac and prognosis and other information.Results There were 62 fetal CDH cases after prenatal evaluation, 33 cases in the moderate and severe group, and 29 cases in mild group.Gender composition, gestational age, birth weight, hernia affected side and hernia sac showed by MRI in two groups were not statistically significant (all P>0.05).The proportion of neonatal Apgar score at 5 min <7 and liver herniation was higher in moderate-to-severe CDH group; The initial diagnosed gestational age, o/e LHR, o/e TFLV, percentage of predicted lung volume (PPLV) and the survival rate were lower in moderate-to-severe CDH group (all P<0.05).The extracorporeal membrane oxygenation (ECMO) indication rate and incidence of persistent pulmonary hypertension of newborn (PPHN) were higher in moderate-to-severe CDH group (all P<0.05).Conclusion The grading of different degrees of fetal diaphragmatic hernia is related to clinical prognosis. Prenatal evaluation is helpful for grading the severity of fetal diaphragmatic hernia patients, and provides the basis for prenatal consultation and planning the treatment for the patients after birth.
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Memo
收稿日期:2020-09-24。
基金项目:广东省自然科学基金-面上项目（编号：2020A1515010296）
通讯作者:吕俊健,Email:13538787151@163.com