Gao Zhipeng,Lin Gang,Ju Li.Giant cell tumor of tendon sheath in children: a report of 2 cases and literature review[J].Journal of Clinical Pediatric Surgery,,20():562-568.[doi:10.12260/lcxewkzz.2021.06.011]
Giant cell tumor of tendon sheath in children: a report of 2 cases and literature review
- Keywords:
- Giant Cell Tumor of Tendon Sheath/DI; Giant Cell Tumor of Tendon Sheath/SU; Antineoplastic Combined Chemotherapy Protocols; Recurrence; Child
- CLC:
- R364.23;R979.1
- Abstract:
- Objective To explore the clinical manifestations,pathological changes and treatments of giant cell tumor of tendon sheath (GCTTS) in children aged under 10 years so as to improve its understanding.Methods Two cases of GCTTS were selected from our hospital while 29 more cases retrieved from the databases of Wanfang,Weipu,CNKI,PubMed and Medline.Results Among 31 GCTTS children,there were 14 boys and 17 girls with a mean age of 91(24-120) months.One major clinical manifestation was painless mass (n=12,38.7%) and the most common sites included knee joints (n=12,38.7%) and fingers (n=10,32.3%).Ultrasound was manifested mostly as hypoechoic mass.The positive rate of radiographic examination was not high (34.6%).And osteolytic bone destruction and soft tissue mass were visualized.Computed tomography (CT) revealed bone destruction accompanied by soft tissue swelling.The predominant findings of magnetic resonance imaging (MRI) were low-to-moderate signal intensity on T1-weighted images and low signal intensity on T2-weighted images.The mean postoperative follow-up period was 38(1-156) months.There was only one confirmed case of postoperative recurrence.Conclusion Pediatric GCTTS is quite rare.Preoperative radiograph,ultrasound and CT/MRI examinations are helpful for an initial diagnosis of GCTTS.However,histopathological examination is required for a definite diagnosis.Initial standardized surgery is vital for the treatment of GCTTS and long-term follow-ups should be strengthened.
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收稿日期:2020-05-27;。
通讯作者:林刚,Email:njchlg@126.com