Xiao Xuwen,Qu Jiangbo,Shi Hui,et al.Evaluation of exercise capacity in children after cardiac sugical operation[J].Journal of Clinical Pediatric Surgery,,20():538-544.[doi:10.12260/lcxewkzz.2021.06.007]
Evaluation of exercise capacity in children after cardiac sugical operation
- CLC:
- R541.1;R332.1
- Abstract:
- Objective To evaluate and compare the physical fitness of children with different severity of cardiac defect with their healthy peers.Methods For this cross-sectional observational study,502 children after operation for congenital heart disease (CHD) and 186 healthy children as controls were recruited.The age was 6-18 years.Complete cardiopulmonary exercise test (CPET) was performed.Based upon diagnostic characteristics and surgical methods,CHD children were further assigned into three subgroups of simple CHD (SCHD),complex CHD (CCHD) and total cavopulmonary connection (TCPC).Physical fitness was compared between groups using generalized linear model and multiple linear regression analysis.Results As compared with age/gender-adjusted healthy controls,SCHD,CCHD and TCPC subgroups had accordingly graded down values of %predicted VO2max (0.98±0.15 vs.0.90±0.12 vs.0.82±0.15 vs.0.72±0.13,P<0.05).The proportion of %predicted VO2max above 80% in the subgroups of SCHD,CCHD and TCPC were (88% vs.65% vs.27.9%,P<0.001).VO2max decreased by 2.26 ml/kg/min per year in CHD children and the corresponding % predicted reference diminished by 5.7%.Children with TCPC had the highest mean reduction of VO2max and %predicted VO2max per year of age (3.05 mL/kg/min,corresponding 8.3%). Conclusion Although the mean overall physical fitness of children with simple/complex defect after biventricular correction are significantly different from healthy population,they are close to normal (>80%predicted VO2max).However,TCPC group has a much lower exercise capacity.
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Memo
收稿日期:2021-03-28;。
基金项目:广州市高水平临床重点专科项目
通讯作者:崔彦芹,Email:2968037903@qq.com