Zhu Yifan,Jiang Qi,Hu Jie,et al.Outcomes of surgical treatments of congenital aortic stenosis in 67 infants[J].Journal of Clinical Pediatric Surgery,,20():512-517.[doi:10.12260/lcxewkzz.2021.06.003]
Outcomes of surgical treatments of congenital aortic stenosis in 67 infants
- Keywords:
- Aortic Valve Stenosis/CN; Aortic Valve Stenosis/SU; Heart Valve Prosthesis Implantation; Treatment Outcome
- CLC:
- R541.1;R493.28;R654.2
- Abstract:
- Objective Congenital aortic stenosis (AS) is a common congenital heart disease with a lifelong hazard of secondary interventions.This study was intended to explore the experience of surgical repair of aortic stenosis in infants.Methods Retrospective review was performed for clinical data of AS infants undergoing aortic repair from January 2008 to December 2020.And early and long-term valvular function,mortality and freedom from reoperation and aortic valve replacment (AVR) were analyzed.Results The median age of 67 patients undergoing surgical valve repair was 140(107-246) days and median operative weight 6.2(4.6-75) kg.And 27 cases were of biscuspid.The mean peak gradient across the valve was (70.2±24.5) mmHg and 1 child developed moderate aortic insufficiency.There was 1 early mortality and 1 late mortality.The mean follow-up period was (5.4±3.2) years.Time-related survival at 10 year was 95.8%.Freedom from reoperation and AVR was 72.7% and 78.9% respectively.Multivariate analysis revealed that Z-score of aortic annulus[HR 0.302,95%CI(0.091,1.006),P=0.031]was an independent risk factor of reoperation.Conclusion Congenital aortic valve repair in infants is both safe and effective to provide enough time to achieve a more definitive solution.Hypoplasty of aortic annulus increases reoperative hazard.
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Memo
收稿日期:2021-03-10;。
基金项目:上海聚德慈善基金资助项目
通讯作者:张海波,Email:zhanghaibosh@126.com