Wang Guannan,Song Hongcheng,Liang Haiyan,et al.Analysis of clinical characteristics and characteristics of ovarian testicular dysplasia[J].Journal of Clinical Pediatric Surgery,,19():1021-1025.[doi:10.3969/j.issn.1671-6353.2020.11.012]
Analysis of clinical characteristics and characteristics of ovarian testicular dysplasia
- CLC:
- R726.9;R691.1
- Abstract:
- Objective To explore the clinical characteristics of ovotesticular disorders of sex development in children.Methods The clinical data were retrospectively reviewed for 60 hospitalized children with ovotesticular disorders of sex development from January 2007 to December 2017.Results Social gender:42 boys and 18 girls.Most of them had abnormal external genitalia.There were 46,XX DSD (n=52),46,XY DSD (n=3) and sex chromosome DSD (n=5).Forty-eight children were examined preoperatively by pelvic and gonadal ultrasonography.Underdeveloped uterus (n=32) and vagina (n=22) were detected.Gonadal biopsy was performed (n=60).The total number of gonads was 120,including ovotestes (n=74),testes (n=16) and ovaries (n=30).Exploration of gonads revealed bilateral type (n=19),ovotesticularplus ovary or testis (n=36),unilateral ovary and contralateral testis (n=5).Among 33 cases of surgical interventions,22 underwent penile straightening and urethroplasty.Clitoris correction was performed (n=11).Conclusion The clinical characteristics of ovotesticular disorders of sex development are diverse and easily missed.Thus clinicians should stay vigilant.Currently there is still a great controversy on choosing gender and operative timing.
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Memo
收稿日期:2019-01-20。
通讯作者:宋宏程,Email:songhch1975@126.com