Wu Shuihua,Chen Zhaohui,Fan Shuangshi,et al.Microsurgery of infantile intracranial aneurysm in a 2-month-old child with a literature review[J].Journal of Clinical Pediatric Surgery,,19():523-527.[doi:10.3969/j.issn.1671-6353.2020.06.012]
Microsurgery of infantile intracranial aneurysm in a 2-month-old child with a literature review
- Keywords:
- Giant Intracranial Aneurysm/SU; Microsurgery; Infant
- CLC:
- R616.2;R651.1+2;725.4
- Abstract:
- Objective To explore the clinical characteristics,diagnostic and therapeutic strategies,pathological characteristics and prognosis of infantile intracranial aneurysm (IIA).Methods Retrospective analysis was performed for clinical data of a 2-month-old IIA child.And the relevant literature reports were retrieved from the databases of PubMed,SpringerLink,Google Scholar,CBM,CNKI,WANFANG and CQVIP.Results In this study,a 2-month-old child underwent transcranial exploration and clipping resection of intracranial aneurysms.Two follow-ups were conducted at 6 and 12 months.With decent nutrition and development,the girl had no obvious clinical symptoms.Her intelligence was the same as normal children of the same age.No obvious abnormality was detected by MRI+MRA.One related literature was retrieved.A total of 7 children were included.The ratio of boy to girl was 1:6 and the average age 4.29 months.The initial clinical manifestation was epilepsy (n=6) and drowsiness (n=1).The location of aneurysm was middle cerebral artery (n=6) and internal carotid artery (n=1).The imaging manifestations were cerebral parenchymal hemorrhage (n=5),subdural hemorrhage (n=1) and subarachnoid hemorrhage (n=1).Fisher’s grade was Ⅱ (n=1) and Ⅳ (n=6).The average size of aneurysms was 0.99 cm and the largest 1.5 cm.The procedure was microscopic clipping craniotomy (n=6,85.7%) and microscopic resection (n=1,14.3%).The prognosis was normal (n=3) and partial limb dysfunction (n=4).Conclusion IIA is quite rare.And its mechanism of disease onset is different from that of adults.Currently the major treatment is microsurgical craniotomy and its prognosis is better than that of adults.
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Memo
收稿日期:2019-08-20。
基金项目:湖南省出生缺陷防治科技重大专项（编号：2019SK1010）；湖南省卫生健康委员会一般项目（编号：B2017118）
通讯作者:沈沉浮,Email:cf_shen@126.com