Fan Ming,Mo Xuming,Chen Jun,et al.Clinical efficacy of mitral valve insufficiency reconstruction in children[J].Journal of Clinical Pediatric Surgery,,19():513-517.[doi:10.3969/j.issn.1671-6353.2020.06.010]
Clinical efficacy of mitral valve insufficiency reconstruction in children
- Keywords:
- Mitral Valve Insufficiency; Valvuloplasty; Treatment Outcome; Child
- CLC:
- R726.1;R725.4;R542.5+1
- Abstract:
- Objective To review the clinical efficacy of mitral valve reconstruction for mitral regurgitation in children.Methods From January 2012 to January 2019,clinical data were collected for 202 children with congenital mitral insufficiency undergoing mitral reconstruction.The improvements of left ventricular function and mitral regurgitation before and after surgery were evaluated by echocardiography and the follow-up outcomes were analyzed.There were 84 boys and 118 girls with an operative age of(21.2±33.3)(1-179)months and a body weight of(9.92±6.75)(3.2-49)kilogram.There were normal valve activity(n=112),valve prolapse(n=54)and abnormal valve activity(n=36).All children underwent mitral reconstructions(valve repairing,ring enlargement & double-hole plasty,etc.)during cardiopulmonary bypass (CPB) at low-moderate temperatures. The CPB time was (75.89±51.36) min and the mean aortic blocking time (45.65±17.89) min. Other concurrent cardiac malformations were corrected simultaneously. Results Without any intraoperative mortality,there were early(n=5)and late(n=3)postoperative death.Among 15 cases of multiple reconstruction,there was one case of death.The average follow-up period was(19.49±17.48)(1-68)months.All children underwent echocardiography for evaluating the differences in left ventricular and mitral valve function before and after surgery.The parameters of left ventricular end diastolic dimension(LVDD),left atrial dimension(LAD)and main pulmonary artery dimension(MPA)significantly improved as compared with those before surgery(P<0.05).And cardiac function classification of New York Heart Association(NYHA)significantly improved at 1 year after surgery as compared with that before surgery(P<0.05).The difference was statistically significant(P<0.05).Conclusion Mitral valve reconstruction improves mitral valve insufficiency in children and has a satisfactory clinical efficacy.
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Memo
收稿日期:2019-10-03。
基金项目:十三五国家重点研发计划重大项目（编号：2016YFC1101000）；"先天性心脏病诊疗技术、疗效评价及康复的综合研究"项目子课题"改善法洛四联症远期预后综合研究及应用推广"课题（编号：81370279）
通讯作者:莫绪明,Email:mohsumingl5@sina.com