Luo Zhendong,Zheng Manna,Li Jiahao,et al.Risk factors for perioperative complications of pediatric retroperitoneal teratoma[J].Journal of Clinical Pediatric Surgery,,19():347-352.[doi:10.3969/j.issn.1671-6353.2020.04.013]
Risk factors for perioperative complications of pediatric retroperitoneal teratoma
- CLC:
- R726.1;R735.4
- Abstract:
- Objective Pediatric retroperitoneal teratoma is relatively rare.However,its surgical removal is associated with a high occurrence rate of perioperative complications.The present study was intended to explore the features of predicting perioperative complication risks and lowering the perioperative complications.Methods Between May 2000 and December 2017,a total of 152 pediatric retroperitoneal teratomas were resected.There are 102 girls and 50 boys with a median age of 5.7 months.Such patient characteristics as gender,age,weight,clinical symptoms,alpha fetoprotein level,radiographic features,intraoperative findings,pathological results and perioperative complications were analyzed.Results Among them,63/152 children (42%) developed 84 perioperative complications,including 79 intraoperative and 5 postoperative complications.Among 113 children with preoperative CT/MRI data,112(99%),111(98%),113(100%) and 28(25%) had arterial distortion,venous distortion,organ distortion and vascular encasement respectively.Univariate analysis revealed that age >1 year and higher body weight were two preventive factors of perioperative complications (OR=0.29,95%CI:0.12-0.71; OR=0.87,95%CI:0.78-0.97).Venous distortion (OR=1.52,95%CI:1.15-2.00),organ distortion (OR=1.74,95%CI:1.23-2.47),vascular encasement (OR=1.53,95%CI:1.06-2.19),tumors beyond midline (OR=2.91,95%CI:1.28-6.60) and left-sided tumor (OR=2.01,95%CI:0.99-4.08) would elevate the risks of perioperative complications.Based upon multivariate analysis,only vascular encasement (OR=1.45,95%CI:1.00-2.10) and organ distortion (OR=1.69,95%CI:1.19-2.41) were significantly associated with an elevated rate of perioperative complications.Conclusion Resection of pediatric retroperitoneal teratoma is associated with a high incidence of perioperative complications.And vascular encasement and organ distortion are significantly associated with higher surgical risks.
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Memo
收稿日期:2019-01-02。
基金项目:国家自然科学基金（编号：81602199）
通讯作者:邹焱,Email:monknut@126.com