Zhang Junqi,Geng Hongquan.Recent advances in renal function evaluation and outcome prediction of pediatric hydronephrosis[J].Journal of Clinical Pediatric Surgery,,19():193-198.[doi:10.3969/j.issn.1671-6353.2020.03.001]
Recent advances in renal function evaluation and outcome prediction of pediatric hydronephrosis
- Keywords:
- Hydronephrosis; Ureteropelvic Junction Obstruction; Ultrasonography; Diuretic Renogram; Magnetic Resonance Imaging
- CLC:
- R726.9;R692.7;R445.1
- Abstract:
- Hydronephrosis of children are generally conservatively managed while surgical intervention is only indicated whenever necessary.However,the management protocol has remained controversial.The diagnostic and predictive values of multiple examinations and surgical indications and timing are not standardized.Examinations of hydronephrosis include ultrasound,diuretic renogram and magnetic resonance urography (MRU).Cut-off values,ratio/index,grading and scoring systems from observational analysis of clinical data help to define the requirements of surgery and the necessities of continuing observations.Currently none of the above modalities dominates prominently in sensitivity and specificity.Novel technology of data analysis such as machine learning has been applied for boosting the diagnostic and predictive capacities of ultrasound and renogram.Clinical application of urinary biomarker is also under exploration.We here reviewed and evaluated recent advances of different diagnostic methods in renal function estimation and outcome prediction.
References:
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Memo
收稿日期:2019-12-27。
基金项目:上海市卫生系统优秀学科带头人培养计划（编号：2017BR061）
通讯作者:耿红全,Email:genghongquan@xinhuamed.com.cn