Hou Fang,Chen Jidong,Xia Meng,et al.Polidocanol injection under ultrasonic guidance for pediatric extremity venous malformations[J].Journal of Clinical Pediatric Surgery,,18():629-634.[doi:10.3969/j.issn.1671-6353.2019.08.003]
Polidocanol injection under ultrasonic guidance for pediatric extremity venous malformations
- Keywords:
- Venous Malformations; Polidocanol; Injections; Therapy; Ultrasonic Guidance; Child
- CLC:
- R732.2;R453
- Abstract:
- Objective To explore the therapeutic efficacies and complications of injecting polidocanol for extremity venous malformations (VM) in children.Methods Fifty-three children with extremity VM received injections of polidocanol under ultrasonic guidance between January 2013 and May 2018.For comparing the therapeutic efficacies of different locations or distributions of VMs,the changes of lesion size,symptoms and complications were recorded.Results The mean age was (3.8±3.1) years.The sites of VM were upper extremity (n=31) and lower extremity (n=22).The lesions were focal (n=41) and diffuse (n=12).They received a total of 96 treatment sessions.The mean session was 1.8±0.9 per patient.After treatments,the outcomes were excellent (n=10),good (n=29),fair (n=11) and poor (n=3).And 22(70.97%) upper extremity and 17 (77.27%) lower extremity VM children had excellent/good outcomes.There was no statistical difference (χ2=0.263,P=0.608); 34(82.93%) focal and 5(41.67%) diffuse VM children had excellent/good outcomes.There were statistical differences (χ2=6.146,P=0.013).During and after treatments,the session number was bradycardia (n=3),hypotension (n=2),local pain (n=31),local swelling (n=87),fever (n=30) and transient local numbness (n=5).During a mean follow-up period of (9.4±6.5) months,there was no recurrence.Conclusion Polidocanol injection under ultrasonic guidance is both safe and effective for superficial,small and medium-sized extremity VMs in children.
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Memo
收稿日期:2019-04-22。
基金项目:国家自然科学基金青年基金（编号：81300238）；四川省科技厅青年基金（编号：2016JQ0059）；四川省科技厅重点研发项目（编号：2017FZ0040）；四川省卫生和计划生育委员会科研基金（编号：16PJ449）；中央高校科研基金（编号：ZYGX2016J171）
通讯作者:刘文英,Email:wenyingl@126.com