Chen Pengyuan,Zhou Chaoran,Li Gang.Interventional treatment of children with congenital heart disease with a second-generation Cera patent ductus arteriosus occluder[J].Journal of Clinical Pediatric Surgery,,18():573-578.[doi:10.3969/j.issn.1671-6353.2019.07.011]
Interventional treatment of children with congenital heart disease with a second-generation Cera patent ductus arteriosus occluder
- Keywords:
- Ductus Arteriosus patent; Heart Desease/CN
- CLC:
- R725.4;R540.4+6
- Abstract:
- Objective To explore the efficacy of second-generation Cera patent ductus arteriosus(PDA) occluder in the interventional treatment of congenital heart disease(CHD) in children and provide a theoretical basis for managing CHD in children.Methods Forty-six hospitalized CHD children from November 2016 to November 2017 were selected and randomly divided into ADOⅠand ADOⅡgroups(n=23 each).Duration of intensive care unit(ICU) stay,imaging of echocardiography and statistic differences of erythrocyte,hematocrit and hemoglobin counts at discharge and 1/3 months post-discharge were compared.Results Tracheal catheter removal time and ICU stay duration were significantly shorter in ADOⅡgroup than those in ADOⅠgroup(P<0.05).As demonstrated by echocardiographic monitoring results before and after treatment,ejection fraction,left ventricular fractional shortening and stroke output were significantly higher at 1/3 months post-discharge in ADOⅡgroup than those in ADOⅠgroup.And end-diastolic left atrium diameter was significantly lower than that of ADOⅠgroup.At discharge and 1/3 months post-discharge,two groups had statistically significant differences in erythrocyte,hematocrit and hemoglobin count(P<0.05).As for treatment outcomes,ADOⅠand Ⅱ groups had an effective rate of 82.61% and 95.65% respectively and the difference was statistically significant(P<0.05).Conclusion The second-generation Cera PDA occluder offers better intervention of CHD children than its first-generation cousin.Wider clinical popularization is warranted.
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Memo
收稿日期:2018-10-27。
基金项目:四川省卫生厅科研项目（编号：17PJ264）
通讯作者:陈芃螈,Email:cpyhigh@qq.com