Sun Song,Zhu Ye,Dong Kuiran,et al.Treatment of esophageal perforation caused by foreign bodies in children: single center clinical experience[J].Journal of Clinical Pediatric Surgery,,18():456-461.[doi:10.3969/j.issn.1671-6353.2019.06.005]
Treatment of esophageal perforation caused by foreign bodies in children: single center clinical experience
- Keywords:
- Hernia; Hiatal/TH; Foreign Bodies; Clinical Protocols; Child
- CLC:
- R768.3+2;R768.3;R655.4
- Abstract:
- Objective As a rare pediatric disease,esophageal perforation may lead to such a fatal complication as mediastinal infection.Currently there is no consensus on its treatment. Methods Retrospective analysis was performed for clinical data of 15 children with esophageal perforation caused by foreign body between January 1,2013 and December 31,2018.And the types of foreign body,major symptoms,short/long-term complications,surgical interventions and prognosis were summarized.Results The most common foreign bodies included button batteries (n=5),fish bones (n=4) and coins (n=3).Major presenting symptoms included fever (n=9),bucking (n=8),cough with sputum (n=8),dysphagia (n=6),refusal of food (n=5) and neck swelling (n=4).And the site of perforation was upper (n=12),middle (n=1) and lower (n=2).Severe infections occurred in 12 of them.And the most common complications were pneumonia (n=10),cervical soft tissue infection (n=7) and mediastinal infection (n=5).Surgical drainage of neck or mediastinal abscess was performed in 5 cases.Thoracotomic removal of abscess and foreign body was performed in 2 cases due to inadequate drainage of thoracic empyema.Two cases were treated with titanium clip under gastroscope.The procedures included gastrostomy (n=8),jejunal nutrition tube implantation (n=4) and nasogastric tube implantation under gastroscope (n=2).Esophageal perforation healed spontaneously in 11 children,3 cases of esophageal stenosis were cured by dilatation and 1 child underwent pyloroplasty due to gastroparesis.Esophagotracheal fistula repair was performed in 2 cases after 3-6 months.One case of continuous esophageal pleural fistula was cured by esophageal stent implantation.One child died from infection.Ten children were followed up for 3 months to 2 years and there was no other complication. Conclusion Button batteries,fish bones and coins are the most common foreign bodies causing esophageal perforation in children.Fever,bucking,cough and other respiratory symptoms are early warning signs of esophageal perforation.Most esophageal perforations heal without surgical repair and surgical intervention is limited to removing foreign bodies and draining abscesses.Titanium clip occlusion in early stage may aid the healing of esophageal perforation.With reasonable treatments,most children with esophageal perforation caused by foreign bodies may obtain an excellent prognosis.
References:
1 Al Lawati TT,Al Marhoobi R.Patterns and complications of ingested foreign bodies in omani children[J].Oman Med J,2018,33(6):463-467.DOI:10.5001/omj.2018.86.
2 Bernadette NN,Ze JJ,Pondy AO,et al.Long standing esophageal perforation due to foreign body impaction in children:a therapeutic challenge in a resource limited setting[J].Case Rep Pediatr,2017,2017:9208474.DOI:10.1155/2017/9208474.
3 Rybojad B,Niedzielska G,Niedzielski A,et al.Esophageal foreign bodies in pediatric patients:a thirteen-year retrospective study[J].Scientific World Journal,2012,2012:102642.DOI:10.1100/2012/102642.
4 Peters NJ,Mahajan JK,Bawa M,et al.Esophageal perforations due to foreign body impaction in children[J].J Pediatr Surg,2015,50(8):1260-1263.DOI:10.1016/j.jpedsurg.2015.01.015.
5 Altokhais TI,Al-Saleem A,Gado A,et al.Esophageal foreign bodies in children:Emphasis on complicated cases[J].Asian J Surg,2017,40(5):362-366.DOI:10.1016/j.asjsur.2015.12.008.
6 Chen T,Wu HF,Shi Q,et al.Endoscopic management of impacted esophageal foreign bodies[J].Dis Esophagus,2013,26(8):799-806.DOI:10.1111/j.1442-2050.2012.01401.x.
7 Sung SH,Jeon SW,Son HS,et al.Factors predictive of risk for complications in patients with oesophageal foreign bodies[J].Dig Liver Dis,2011,43(8):632-635.DOI:10.1016/j.dld.2011.02.018.
8 Vieira E,Cabral MJ,Goncalves M.Esophageal perforation in children:a review of one pediatric surgery institution’s experience (16 years)[J].Acta Med Port,2013,26(2):102-106.
9 Fattahi MS,Nouri DM,Fattahi AS,et al.Surgical management of early and late esophageal perforation[J].Asian Cardiovasc Thorac Ann,2018,26(9):685-689.DOI:10.1177/0218492318808199.
10 Kaman L,Iqbal J,Kundil B,et al.Management of Esophageal Perforation in Adults[J].Gastroenterology Res,2010,3(6):235-244.DOI:10.4021/gr263w.
11 陈硕,李辉,胡滨,等.食管异物所致食管穿孔合并纵隔脓肿的诊断与治疗[J].中华胸心血管外科杂志,2017,33(7):433-434.DOI:10.3760/cma.j.issn.1001-4497.2017.07.013. Chen S,Li H,Hu B,et al.Diagnosis and treatment of mediastinal abscess and esophageal perforation caused by foreign bodies[J].Chin J ThoracCardiovascSurg,2017,33(7):433-434.DOI:10.3760/cma.j.issn.1001-4497.2017.07.013.
12 Tsukiyama A,Tagami T,Kim S,et al.Use of 3-dimensional computed tomography to detect a barium-masked fish bone causing esophageal perforation[J].J Nippon Med Sch,2014,81(6):384-387.DOI:10.1272/jnms.81.384.
13 Mishra B,Singhal S,Aggarwal D,et al.Non operative management of traumatic esophageal perforation leading to esophagocutaneous fistula in pediatric age group:review and case report[J].World J Emerg Surg,2015,10:19.DOI:10.1186/s13017-015-0012-y.
14 Onwuka EA,Saadai P,Boomer LA,et al.Nonoperative management of esophageal perforations in the newborn[J].J Surg Res,2016,205(1):102-107.DOI:10.1016/j.jss.2016.06.027.
15 Karabulut R,Turkyilmaz Z,Sonmez K,et al.Conservative treatment with octreotide to provide early recovery of children with esophageal perforation[J].Thorac Cardiovasc Surg,2018,66(5):396-400.DOI:10.1055/s-0037-1600518.
16 Rentea RM,St PS.Neonatal and pediatric esophageal perforation[J].Semin Pediatr Surg,2017,26(2):87-94.
17 Hesketh AJ,Behr CA,Soffer SZ,et al.Neonatal esophageal perforation:nonoperative management[J].J Surg Res,2015,198(1):1-6.DOI:10.1016/j.jss.2015.05.018.
18 Cross MR,Greenwald MF,Dahhan A.Esophageal perforation and acute bacterial mediastinitis:other causes of chest pain that can be easily missed[J].Medicine (Baltimore),2015,94(32):e1232.DOI:10.1097/MD.0000000000001232.
19 Paspatis GA,Dumonceau JM,Barthet M,et al.Diagnosis and management of iatrogenic endoscopic perforations:European Society of Gastrointestinal Endoscopy (ESGE) Position Statement[J].Endoscopy,2014,46(8):693-711.DOI:10.1055/s-0034-1377531.
20 van Boeckel PG,Dua KS,Weusten BL,et al.Fully covered self-expandable metal stents (SEMS),partially covered SEMS and self-expandable plastic stents for the treatment of benign esophageal ruptures and anastomotic leaks[J].BMC Gastroenterol,2012,12:19.DOI:10.1186/1471-230X-12-19.
21 Krom H,Visser M,Hulst JM,et al.Serious complications after button battery ingestion in children[J].Eur J Pediatr,2018,177(7):1063-1070.DOI:10.1007/s00431-018-3154-6.
22 Varga A,Kovacs T,Saxena AK.Analysis of Complications After Button Battery Ingestion in Children[J].Pediatr Emerg Care,2018,34(6):443-446.DOI:10.1097/PEC.0000000000001413.
23 Govindarajan KK.Esophageal perforation in children:etiology and management,with special reference to endoscopic esophageal perforation[J].Korean J Pediatr,2018,61(6):175-179.DOI:10.3345/kjp.2018.61.6.175.
Memo
收稿日期:2019-04-20。
基金项目:国家自然科学基金(编号:81700450);第四批上海市青年医师培养资助计划
通讯作者:郑珊,Email:szheng@shmu.edu.cn;陈功,Email:1973.cc@163.com