Chen Guangjie,Tian Hongjuan,Wu Dehua,et al.Role of masculinization score in the assessment of 46,XY disorders of sex development[J].Journal of Clinical Pediatric Surgery,,18():202-205.[doi:10.3969/j.issn.1671-6353.2019.03.008]
Role of masculinization score in the assessment of 46,XY disorders of sex development
- Keywords:
- Gonadal Dysgenesis; 46; XY/Embryo; Androgenization; Gender Identity
- CLC:
- R726.9;R691.1
- Abstract:
- Objective To evaluate the role of masculinization score in the assessment of 46,XY disorders of sex development (DSD).Methods With a specially devised scoring system,external masculinization score (EMS) and internal masculinization score (IMS) were used for assessing 416 physical examination boys and 106 cases of 46,XY DSD.Results In physical examination boys,415(99.8%) had EMS ≥ 11.Among affected children,sex of rearing was boy (n=81) and girl (n=25).The median scores of EMS and IMS were 6(3,10),9(9,9) and 2(1.5,2),9(7,9) points respectively.Statistical difference existed in inter-gender EMS score.Boy group had a higher score(P=0.000);There was no statistical difference in inter-gender IMS score.For IMS score,the incidence of uterus,urogenital sinus,vagina/prostatic cyst and deficiency of deferent duct were higher in boy than those in girl (P<0.05).Conclusion EMS/IMS provides a objective,standardized and simple format of assessing the clinical features of children with 46,XY DSD.
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Memo
收稿日期:2018-12-28。
基金项目:国家重点研发计划项目（编号：2018YFC1002700）；浙江省教育厅基金资助项目（编号：Y201225816）
通讯作者:唐达星,Emai:tangdx0206@zju.edu.cn