Xiong Zhu,Zeng Shuaidan,Liu Dan,et al. Efficacy of elongating intramedullary rods for lower extremity fractures in osteogenesis imperfecta children:a metaanalysis.[J].Journal of Clinical Pediatric Surgery,,18():18-24.
Efficacy of elongating intramedullary rods for lower extremity fractures in osteogenesis imperfecta children:a metaanalysis.
Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R]
volume:
第18卷
Number:
2019 01
Page:
18-24
Column:
论著
Date of publication:
2019-01-20
- Keywords:
- ; Child; Elongating Intramedullary Rods; Osteogenesis Imperfecta; Lower Extremity Fractures
- Document code:
- A
- Abstract:
- ObjectiveTo evaluate the safety profile of elongating intramedullary rods for lower extremity fractures in osteogenesis imperfect (OI) children to provide rationales for future application in China.MethodsWe systematically searched the electronic databases of PubMed,EmBase,Cochrane library,Wanfang Data Resource System of Digital Periodicals and Chinese Journal Full text Database with the inception of January 2018.All processes followed the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA).And inclusion and exclusion standards were implemented.The summary results were calculated by a random effect model.ResultsA total of 8 studies were included into the final cohort.There were 258 lower extremities using the elongating intramedullary rod approach.The mean age was 3.1-8.0 years and the followup period 17-228 months.The rate of rodrelated complications was 25.00% (95% CI:15.00%-34.00%) and most cases were related with rod migration (13.54%).Egger and Begg tests showed no significant publication bias (PEgger:0.248;PBegg:0.386).The rate of bonerelated complications was 16.00% (95% CI:9.00%-23.00%) and refractures were predominant (8.43%).However,Egger and Begg tests showed significant publication bias (PEgger:0.040;PBegg:0.086).The reoperative rate was 23.00% (95% CI:12.00%-35.00%).And Egger and Begg tests also showed no significant publication bias (PEgger:0.734;PBegg:0.806).ConclusionDuring elongating intramedullary rod in OI surgery,rod migration and refracture remain two major postoperative complications.However,comparing with nonelongating intramedullary rodding,the efficacy has obviously improved.With constant development of surgical technique and internal fixation system,this procedure offers a better life quality.
Last Update:
2019-01-22