Yu Xindi,Du Xinwei,Wang Wei,et al. Mortality analyses for children with congenital heart disease after cardiopulmonary bypass.[J].Journal of Clinical Pediatric Surgery,,17():911-916.
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 Mortality analyses for children with congenital heart disease after cardiopulmonary bypass.

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: 第17卷 Number: 2018 12 Page: 911-916 Column: 论著 Date of publication: 2018-12-18
Author(s):
 Yu Xindi; Du Xinwei; Wang Wei; Zhu Deming; Xu Zhuoming; Zhang Haibo.
 Department of Pediatric Thoracic Cardiovascular Surgery,Affiliated Childrens Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China.
Keywords:
 ; Heart Disease/CN;  Extracorporeal Circulation;  Mortality;  Surgical Procedures;  Operative;  Child
Document code:
A
Abstract:
 ObjectiveTo explore the cause of death and the complications of age in 569 deceased children after cardiopulmonary bypass so as to provide rationales for improving the prognosis of congenital heart disease (CHD) after open heart surgery.MethodsFrom 2009 to 2016,569 CHD cases were selected as the observation objects to compare the types of malformation,age,postoperative mortality and complications.ResultsAmong 23,500 cases,569 patients died postoperatively with a mortality rate of 2.42%.Compared with surviviors,CPB time and aortic occlusion time were significantly longer in deceased children and the difference was statistically significant (P<0.05).The mortality rate of CHD children was only 1.68% by 2016.Compared to 2015,besides a slight drop in total number of operations in 2016,the number of cases from 2009 to 2015 has shown an growing trend yearbyyear.Since 2011,as the total number of operations began to increase (compared with 2010,an increase of 349 children),the number of deaths has increased simultaneously,but the mortality rate is still declining.Of all cases,the mortality rate of 6monthold infants was higher while 3monthold counterparts had the highest rate (35.50%).The major causes of death were low cardiac output syndrome(67.74%),respiratory failure (15.93%),multiple organ dysfunction syndrome (11.49%) and cardiac arrhythmia (7.66%).ConclusionThe mortality rate of CHD children is correlated with the complexity of malformation and negatively related with patient age.Protection of heart function is vital for decreasing the postoperative mortality of CHD.
Last Update: 2018-12-18