Wu Yan,Yang Wenping,Zhang Shouhua,et al. Correlation between the expressions of epithelialtomesenchymal transition markers in children with biliary atresia.[J].Journal of Clinical Pediatric Surgery,,17():826-829.
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 Correlation between the expressions of epithelialtomesenchymal transition markers in children with biliary atresia.

Journal of Clinical Pediatric Surgery[ISSN:1671-6353/CN:43-1380/R] volume: 第17卷 Number: 2018 11 Page: 826-829 Column: 专题讨论 Date of publication: 2018-11-20
Author(s):
 Wu Yan; Yang Wenping; Zhang Shouhua; Xu Hongyan; Zeng Songtao; Huang Hui; Xiong Feng; Zeng Hua.
 1.Department of Pathology,Jiangxi Childrens Hospital,Nanchang 330006,China;
Keywords:
 ; Biliary Atresia;  Liver Cirrhosis;  Immunohistochemistry;  Research
Document code:
A
Abstract:
 ObjectiveTo detect the expressions of Ncadherin，Ecadherin,vimentin,SMA and CK19 in biliary aressia and congenital cyst of common bile duct and discuss the relationship with in epithetialtomesenchymal transition.MethodsThe expression of Ncadherin,Ecadherin,vimentin,SMA and CK19 in biliary atresia (n=34) and common bile duct cyst (n=13) were detected by immunohistochemistry SP method.ResultsThe expression ratios of Ncadherin.Ecadherin,vimentin,SMA and CK19 were higher in liver of bile duct than those in common bile duct (P<0.05).ConclusionThe expressions of Ncadherin,vimentin,SMA and CK19 are closely correlated with epithelialtomesenchymal transition.And EMT may be one of important causes of hepatic cirrhosis.
Last Update: 2018-11-23