Xu Chang,Chen Hou-ping,Zhong Lin,et al.Clinical Analysis of Pancreatoblastoma in child.[J].Journal of Clinical Pediatric Surgery,,9():0.
Clinical Analysis of Pancreatoblastoma in child.
- Keywords:
- pancreatoblastoma; alpha-foetoprotein; Child
- Abstract:
- Objective Pancreatoblastoma(PB) is a rare pancreatic tumor that generally affects infants and young children. In this study, three cases of childhood PB are reported to emphasize the clinical course of this rare disease. Methods Three cases of pathologically proven PB treated at West China Hospital were reviewed. Results Abdominal pain and vomiting were observed in one case for the huge size of the tumor. The other tow cases, who were previously well, complained of a mass in the abdomen after a casual physical examination. Elevated serum alpha-foetoprotein(AFP) levels were noted in all cases. Imaging findings indicated well-defined heterogeneous large mass in the left retroperitoneal space. Exploratory laparotomy revealed a large mass, arising from tail of pancreas, not infiltrating the adjacent structures in all cases. Surgery alone with complete excision of the masses was perfumed. The histopathological examination revealed PB. All of these three cases have a good outcome in the follow-up without adjuvant chemotherapy. Conclusions These data suggest that the diagnosis of PB is difficult and should be suspected at palpation of an abdominal mass. AFP may serve as a tumor marker for preoperative diagnosis and postoperative recurrence. PB is a curable tumor and adjuvant chemotherapy may not necessary if the tumor can be excised completely.
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Memo
1，四川大学华西医院小儿外科（成都市，610041），E-mail：xcxcxc52229081@163.com；2，四川大学华西医院病理科（成都市，610041），通讯作者：钟麟，E-mail：zhonglinabc@163.com