Home>> 2026 05
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[Zhang Xintao, Li Hongxing, Tang Weibing]
[Absract] Objective As a relatively common congenital disorder of enteric nervous system development in infants,Hirschsprung disease (HSCR) is a congenital gastrointestinal malformation caused by impaired migration and colonization of neural crest cells.Its causes are a combination of genetic and microenvironmental factors.Further explorations are still required for elucidating its pathogenesis,optimizing therapeutic strategies and managing complications.Single-cell sequencing technology may cha... [MORE...]
[PDF: 857KB](24)
[Group of Pediatric Urology, Branch of Urology, Chinese Medical Association]
[Absract] Objective The global incidence of pediatric urolithiasis is rising,yet its Chinese epidemiological data remain incomplete.Its etiology is rather complex so that it has been associated with metabolic abnormalities,urinary tract malformations and infections; in particular,upper urinary tract calculi may impair renal development in children.Extracorporeal shock wave lithotripsy (ESWL),as one of the important therapeutic modalities for pediatric upper urinary tract calculi,offers the clini... [MORE...]
[PDF: 1416KB](22)
[Xia Xingrong, Liu Yuanmei, Zhou Wankang, Jin Zhu, Tang Chengyan, Huang Lu, Li Zeping, Zhu Daiwei, Gong Yuan, Du Qing, Zheng Zebing]
[Absract] Objective Objective To explore the clinical efficacy of da Vinci robot-assisted laparoscopic Swenson-like total colectomy in older children (age ¡Ý 4 years) with Hirschsprung¡¯s disease (HSCR).Methods From January 2011 to January 2025,retrospective analysis was conducted for the relevant clinical data of 60 operated HSCR children aged ¡Ý4 year.There were 34 boys and 26 girls with an age range of (4-18) year.They were assigned into two groups based upon specific surgical ... [MORE...]
[PDF: 1349KB](20)
[Sun Song, Zheng Shan, Chen Gong, Li Debao, He Weijing, Jiang Jingying, Shen Chun]
[Absract] Objective Objective Tosystematically explore the causes of reoperation after radical surgery for Hirschsprung¡¯s disease (HSCR) and examine the associated risk factors and protective factors.Methods From January 2018 to December 2024,the relevant clinical data were retrospectively reviewed for 507 operated HSCR children.According to whether or not reoperation was required for complications after radical surgery,they were assigned into two groups of reoperation (n[MORE...]
[PDF: 808KB](22)
[Yan Jiayu, Wang Kexin, Chen Yajun]
[Absract] Objective Objective Tosummarize the long-term outcomes of the Soave procedure for Hirschsprung¡¯s disease (HD) and to analyze potential factors affecting long-term prognosis.Methods A retrospective study was conducted on 91 children with HD who underwent the Soave procedure performed by the same surgical team at Beijing Children¡¯s Hospital,Capital Medical University,between January 2011 and December 2015.Telephone follow-up was performed in January 2026,and all patient... [MORE...]
[PDF: 1004KB](23)
[Ma Zhihua, Tang Jie, Li Hongxing, Tang Weibing]
[Absract] Objective Hirschsprung¡¯s disease (HSCR) is a congenital enteric neurodevelopmental disorder characterized by the absence of ganglion cells in the distal intestine,leading primarily to intestinal dysfunction.The disease most commonly affects neonates and infants,with clinical manifestations including difficulty in defecation,poor feeding,inadequate weight gain,and progressive abdominal distension.At present,surgical intervention remains the mainstay of treatment,with the core objective ... [MORE...]
[PDF: 686KB](21)
[Wang Wei¡¯ao, Liu Yuanmei, Zheng Zebing]
[Absract] Objective Injury of intestinal mucosal barrier is one of primary manifestations of intestinal diseases in children,e.g.Hirschsprung-associated enterocolitis (HAEC) and inflammatory bowel disease (IBD).Currently there is a lack of effective measures for promoting the healing and regeneration of intestinal mucosal barrier.As the progenitor cells for intestinal mucosal barrier repair and regeneration,intestinal stem cells (ISCs) have brought hopes for future applications in clinical pract... [MORE...]
[PDF: 637KB](18)
[Ma Yan, Bai Dongsheng]
[Absract] Objective Objective Toexplore the pathological differences between intermittent and persistent hydronephrosis caused by stenosis at the junction of renal pelvis and ureter in children and provide references for its clinical diagnosis and treatment.Methods A retrospective case-control study was conducted for 46 children with ureteropelvic junction obstruction (UPJO) undergoing unilateral dismembered pyeloplasty between September 2017 and March 2024.Based upon the type ... [MORE...]
[PDF: 1281KB](26)
[Wang Zhengyan, Wang Wenjing, Xia Sili, Zhou Jianmin, Lu Shuangquan]
[Absract] Objective Objective Toexplore the detecting value of contrast-enhanced voiding urosonography (ceVUS) plus serum cystatin C (Cys C) in evaluating vesicoureteral reflux (VUR) and associated renal damage in children.Methods A retrospective case series study was conducted,including 458 children with recurrent urinary tract infections hospitalized from December 2019 to March 2025.And ceVUS was employed for assessing VUR grade and confirming the presence of intrarenal reflu... [MORE...]
[PDF: 1270KB](27)
[Fu Xiaobao, Xu Nana, Li Xiaoran, Mi Jun, Wang Peilong, Yang Ningqiang]
[Absract] Objective Objective Toexplore the characteristics and related influencing factors of fever during hospitalization after laparoscopic pyeloplasty (LP) for congenital ureteropelvic junction obstruction (UPJO) in children to provide references for the prevention and intervention of postoperative fever in clinical practices.Methods A retrospective analysis was performed for the relevant clinical data of 143 children with congenital UPJO undergoing primary unilateral LP (w... [MORE...]
[PDF: 591KB](21)
[Liu Hu, Guo Dong, Li Chengxin, Sun Baosheng, Zhang Xuejun]
[Absract] Objective Objective Toevaluate the feasibility,safety,and efficacy of posterior atlantoaxial screw-rod fixation in the treatment of pediatric atlantoaxial instability and dislocation.Methods A retrospective analysis was conducted on 106 patients under 18 years of age who underwent surgery at Beijing Children¡¯s Hospital,Capital Medical University,between January 2012 and January 2022.The cohort included 61 males and 45 females,with a mean age of 6.4 years.The main etio... [MORE...]
[PDF: 807KB](21)
[Liu Denghui1, Li Yong1, Li Ming1, Huang Zhao1, Wen Jiabing1, Tang Xianglian1, Ning Feng2, Yang Guangxian3]
[Absract] Objective Objective Toexplore the clinical characteristics,diagnoses,treatments and prognoses of extracranial mixed germ cell tumor (MGCT) in children.Methods A retrospective analysis was performed on the clinical and follow-up data of 13 children with extracranial mixed germ cell tumors (MGCT) admitted to Affiliated Children¡¯s Hospital,Xiangya School of Medicine,Central South University(Hunan Children¡¯s Hospital),from January to June 2023.The clinical characteristics... [MORE...]
[PDF: 691KB](23)
[Sun Daang1,2, Yu Kechi1, Yang Fengjie3, Wei Xian1, Li Ning1, Wu Xiaojuan1]
[Absract] Objective Objective Toexplore the clinical characteristics of hematologic malignancies complicated by acute abdomen in children and establish its standardized management protocols.Methods From January 2010 to June 2024,retrospective analysis was conducted for the relevant clinical data of 40 children hospitalized with hematological malignancies complicated by acute abdomen.General patient profiles,type of primary disease,clinical manifestations and types of acute abdo... [MORE...]
[PDF: 732KB](21)
[Liao Jiali1, Li Gefang1, He Bo1, Zhang Qun2, Li Ziyu3, You Jiaxin1]
[Absract] Objective Objective Toconstruct predictive models for Staphylococcus aureus (S.aureus) infection using 4 machine learning algorithms based on clinical characteristics and laboratory indicators at admission in children with septic arthritis,aiming to determine the infection status of S.aureus before the availability of etiological test results.Methods A retrospective analysis was conducted on the clinical data of 463 children with septic arthritis admitted to the Child... [MORE...]
[PDF: 3438KB](19)
[Qiu Jiajing, Wang Jingzi, Li Xiaoyu, Dong Jiaqi, He Feiyue, Guo Yunfei, Huang Liqu]
[PDF: 1246KB](19)
[Li Xiazhe1,3, Wang Le2,3, Zhong Zhiyong1,3, Gong Yingxin1,3]
[PDF: 664KB](32)
[Wang Gang1,2, Tang Xueyang1, Zou Li1]
[Absract] Objective Pediatric intervertebral disc calcification (PIDC) is a self-limited disease characterized by calcification of the nucleus pulposus of the intervertebral disc,typically affecting children aged 5-12,and is mostly discovered incidentally.The pathogenesis remains unclear and may be associated with factors including trauma,infection,metabolic disorders,vitamin D overdose,and avascular necrosis.Radiographic findings on X-ray or CT show that calcified lesions are predominantly loca... [MORE...]
[PDF: 656KB](23)
[Dong Zhengyi1, Jiang Weiwei2]
[Absract] Objective Postoperative nausea and vomiting (PONV) is a common clinical complication,with an incidence of approximately 60%-70% in children,which is significantly higher than that in adults.Compared with treatment after onset,clinical practice places greater emphasis on prevention.Preventive strategies for pediatric PONV include establishing pediatric-specific risk scoring systems to predict its occurrence,selecting appropriate anesthesia methods,and implementing multimodal prophylacti... [MORE...]
[PDF: 582KB](21)