[Yu Bingran, Chen Gong]
[Absract] Objective
Hepatoblastoma is the most common primary malignant liver tumor in children.Although significant advancements have been made in early diagnosis,surgical techniques,and platinum-based chemotherapy regimens,some tumors remain unresectable even after chemotherapy.For these advanced or unresectable cases,liver transplantation has emerged as an effective treatment option.In recent years,substantial progress has been achieved in applying liver transplantation for pediatric hepatobl...
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[Xi Jianxin, Chen Yuguo, Geng Xiaochen, Qiu Wei, Lyu Guoyue]
[Absract] Objective
Objective To observe the efficacy of recombinant anti-cluster of differentiation 25 (CD25) humanized monoclonal antibody plus steroid reduction immune induction regimen in preventing acute rejection (AR) in pediatric liver transplant (LT) recipients.Methods Retrospective analysis was conducted for 79 pediatric LT recipients between July 2015 and August 2024.Based upon perioperative immune induction regimens,they were assigned into two groups of full-dose ste...
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[Sun Yan1, Wang Bing1, Gao Sinan1, Dou Xiaojing1, Sun Chao2, Cheng Yue3]
[Absract] Objective
Objective To explore the correlation between intestinal mucosal barrier function impairment and rectal colonization of carbapenem-resistant enterobacteria (CRE) during pediatric liver transplantation (LT) and summarize the general rules of postoperative intestinal mucosal impairment and repairing.Methods From November 1st,2022 to December 31st,2022,40 children with biliary atresia (BA) undergoing LT were assigned into two groups of CRE colonization and non-C...
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[Liu Hui1, Halimulati Huxitaer1, Li Wanfu1, Gao Wei2, Dong Chong2, Sun Chao2, Aerxin Habuding1, Gulimiremu Maimaitijiang1, Ayiguzaili Maimaijiang1, Yeliaman Jiayilawu1, Chen Zhida1, Wang Haoyu1]
[Absract] Objective
Objective To analyze the clinical outcomes of living donor liver transplantation in the treatment of pediatric inborn errors of metabolism (IEM).Methods A retrospective analysis was conducted on the clinical data of 18 pediatric patients with IEM who underwent living donor liver transplantation at the First Affiliated Hospital of Xinjiang Medical University from January 2021 to July 2024 (IEM group).The treatment outcomes and postoperative complications were...
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[Tong Xuan1, Tang Rui1, Li Long2, Lu Qian1]
[Absract] Objective
Objective To explore the efficacy and prognosis of split liver transplantation (SLT) for familial hypercholesterolemia (FH).Methods A single-center retrospective study was conducted for 5 FH children undergoing SLT from September 2020 to March 2022.There were 4 girls and 1 boy with a median age of 11(5-15) year.Clinical and follow-up data were collected,including low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) at pre-operation,Month 1 ...
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[Feng Yong1, Zhou Chonggao1, Xia Renpeng1, Zou Chanjuan1, Xu Guang1, Dong Jie2, Li Bo1]
[Absract] Objective
Objective To compare the efficacy of total laparoscopic versus open Kasai portoenterostomy for type ¢ó biliary atresia (BA).Methods From May 2020 to December 2021,the relevant clinical data were retrospectively reviewed for 14 children undergoing laparoscopic Kasai portoenterostomy and 66 cases undergoing open Kasai portoenterostomy.Two groups were compared with regards to gender,operative age,body weight,preoperative total bilirubin,direct bilirubin,alanine ...
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[Zhao Shimeng1, Cui Xiaowei2, Cao Yanyan3, Qi Can1, Liu Lijun4, Chen Xiaoxiao4, Liu Yingye3, Liu Lei5, Zhou Yun1]
[Absract] Objective
Objective To compare the postoperative complications and outcomes of feminizing genitoplasties (FG) in girls with congenital adrenal hyperplasia (CAH) and masculinized external genitalia across different age groups.Methods We conducted a retrospective analysis of 32 girls with CAH and masculinized genitalia who underwent FG procedures at Hebei Children¡¯s Hospital from March 2010 to August 2022.Patients were divided into two groups based on age:infants and yo...
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[Chen Weiming, Bai Jianxi, Zhang Bing, Wu Dianming, Fang Yifan]
[Absract] Objective
Objective To establish and validate a clinical prediction model assessing the survival of children with neuroblastoma (NB). Methods The relevant clinical data were collected from NB children between 2000 and 2019 from the database of Surveillance,Epidemiology and End Results (SEER).The primary cohort was randomized into two sets of training (n=987) and validation (n=493).The prognostic effects of variables were examined with a Cox proportional ...
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[Pan Yongdong, Fang Xiaoliang, Xu Guofeng]
[Absract] Objective
Objective To investigate the risk factors for complications following reoperation for hypospadias.Methods A retrospective analysis was conducted on the clinical data of children who underwent reoperation for hypospadias at Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine between December 2019 and December 2021.Patients were divided into two groups based on whether they experienced complications after the final surgery:the compli...
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[Wang Kuiliang, Zhang Xu, Luo Gang, Pan Silin]
[Absract] Objective
Objective To evaluate the clinical effect of local injection of papaverine combined with lidocaine in treating acute limb ischemia caused by vascular spasm after cardiac catheterization in infants with congenital heart disease (CHD).Methods A retrospective analysis was conducted on clinical data from infants who developed acute limb ischemia due to vascular spasm after CHD cardiac catheterization at the Heart Center of Women and Children¡¯s Hospital Affiliate...
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[Yin Furui, Wan Jun, Wang Jizhong]
[Absract] Objective
Objective To summarize the clinical characteristics,diagnosis,and treatment of primary omental infarction in children.Methods A retrospective analysis was conducted on 17 pediatric cases of primary omental infarction treated at Tianjin Children¡¯s Hospital from June 2017 to June 2022.The cohort included 14 males and 3 females,with a mean age of 8.5¡À2.7 years (range:4.9-12.8 years).Clinical presentations,laboratory findings,imaging results,treatments,and patho...
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[Zhang Jiyan1, Zhang Xi1, Liu Teng2, Xiao Zhenghui3, Huang Jianbao1, Zhang Xinping3, Zhang Jin1, Duan Xiaojun1]
[Absract] Objective
Objective To summarize the clinical characteristics of primary airway tumors in children and to evaluate the effectiveness and safety of bronchoscopic interventional diagnosis and treatment for these tumors.Methods This retrospective study included 10 pediatric patients diagnosed with primary airway tumors who were hospitalized at Hunan Children¡¯s Hospital between January 2019 and September 2023.Clinical symptoms,imaging findings,pathological results,broncho...
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[Wang Hongli, Xia Jipeng, Zhu Rongkun, Zhang Peng, Hao Xiwei]
[Absract] Objective
Objective To explore the clinical features,diagnoses and therapeutic strategies of complete androgen insensitivity syndrome (CAIS) in children.Methods The relevant clinical data of a child with CAIS were retrospectively reviewed."Complete androgen insensitivity syndrome" was applied as a search term in PubMed,China National Knowledge Infrastructure (CNKI) and WANFANG DATA from January 2013 to October 2023.Along with the relevant literature fulfilling the spe...
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[Lin Zhixiong, He Yuanbing, Liu Mingkun, Fang Yifan, Wu Dianming]
[Shi Boyi, Peng Wei]
[Absract] Objective
Venoarterial extracorporeal membrane oxygenation (V-A ECMO) is primarily used to provide circulatory and respiratory support in patients with severe cardiogenic shock or refractory cardiac arrest.Although it allows the heart to rest for a certain period,the increased left ventricular afterload in some patients can lead to left ventricular dilation,exacerbating myocardial damage and pulmonary edema,which contradicts the fundamental principles of ECMO.Therefore,an appropriate a...
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[Zhu Liling1, Xiao Ting2, Qu Shuangquan2]
[Absract] Objective
Acute lung injury (ALI) and its more severe form,acute respiratory distress syndrome (ARDS),are lung diseases with high mortality rates.They are often complicated by brain injury,significantly affecting treatment and prognosis.Inflammatory plays a pivotal role in the "lung-brain axis" of ALI.As a critical pro-inflammatory factor,extracellular high mobility group box 1 protein (HMGB1) is widely implicated in the pathogenesis of both pulmonary and cerebral injuries.Inhibiting H...
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[Liu Jilan1, Liu Haiyan2]
[Absract] Objective
Klippel Trenaunay syndrome (KTS) is an overgrowth syndrome characterized by capillary malformations,venous malformations,extremity hypertrophy and with or without lymphatic malformations.It frequently occurs in neonates,infants and toddlers.Its etiology and pathogenesis have been associated with mutations in somatic PIK3CA gene.Its clinical manifestations are diverse and affect different organ systems.Currently there is no cure and conservative measures are applied.The major ...
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[Chu Jing]
[Absract] Objective
Wilms tumor (WT) is a malignant embryonal tumor derived from renal blastoid cells.It is characterized by a difficult early diagnosis,frequent recurrence after treatment and a poor prognosis of some pathological subtypes.A combination of clinical profiling,pathological examination and molecular genetic test is indispensable for making an accurate diagnosis,guiding therapy and prognostic prediction.This review summarized the clinicopathologic features,molecular genetics,diagnos...
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