Zhu Ledao,Chen Yang,Zhou Ling,et al.Research advances of exosomes in the treatment of neonatal necrotizing enterocolitis[J].Journal of Clinical Pediatric Surgery,2024,(12):1197-1200.[doi:10.3760/cma.j.cn101785-202211007-017]
外泌体治疗新生儿坏死性小肠结肠炎的研究进展
- Title:
- Research advances of exosomes in the treatment of neonatal necrotizing enterocolitis
- Keywords:
- Enterocolitis; Necrotizing; Exosomes; Infant; Newborn
- 摘要:
- 坏死性小肠结肠炎 (necrotizing enterocolitis,NEC) 是新生儿胃肠疾病中严重疾病之一。尽管目前已经有了多种治疗方法,但NEC的发病率及严重并发症的发生率仍然是困扰临床医师的难题。近年来,外泌体作为一种全新的无细胞疗法,其治疗NEC的潜能正逐渐被挖掘出来。本文阐述外泌体的特征以及外泌体治疗NEC的研究进展,以期为NEC的治疗提供新的参考。
- Abstract:
- Necrotizing enterocolitis (NEC) is one of the most serious gastrointestinal diseases in neonates.Although many treatment methods have been developed for NEC,its incidence rate and serious complications show no significant reduction.Therefore developing new treatment of NEC have remained hotspots.Recently using exosomes as a cell-free treatment attracted growing attention.The characteristics and the latest advances of exosomes in the treatment of NEC were comprehensively reviewed as references for clinical practices.
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备注/Memo
收稿日期:2022-11-4。
基金项目:深圳市医学重点学科(2020—2024—SZXK035)
通讯作者:任锋,Email:renfeng2000@sohu.com