Liang Xingchi,Cheng Shigang,Mao Xiaowen,et al.Laparoscopic resection of cystic neuroblastoma in children: a report of 6 cases[J].Journal of Clinical Pediatric Surgery,2023,22(01):23-27.[doi:10.3760/cma.j.cn101785-202208036-005]
腹腔镜手术治疗儿童囊性神经母细胞瘤
- Title:
- Laparoscopic resection of cystic neuroblastoma in children: a report of 6 cases
- Keywords:
- Neuroblastoma; Laparoscopes; Cystic Fibrosis; Surgical Procedures; Operative; Child
- 摘要:
- 目的 探讨儿童囊性神经母细胞瘤(cystic neuroblastoma,CNB)的诊治及腹腔镜下手术治疗的安全性和有效性。方法 回顾性分析2016年6月至2021年12月华中科技大学同济医学院附属湖北省妇幼保健院外科收治的6例囊性神经母细胞瘤患儿临床资料,6例均行腹腔镜下腹膜后囊性包块切除术;收集患儿术后疗效及远期并发症发生情况。结果 本组6例患儿中,男4例,女2例,均于产前经B超发现腹腔囊性包块;5例成功完成腹腔镜下腹腔囊性包块切除术,1例中转开腹手术。手术年龄8~38d,中位年龄12d;手术时长60~120min,平均87min;术中出血量1~10mL,平均5.6mL;无一例术中输血病例。术后住院时间7~11d,平均9.5d。术后病理检查结果均提示囊性神经母细胞瘤,均未行化疗。随访6~71个月,无一例复发。结论 儿童囊性神经母细胞瘤有良好的生物学特征和预后,为避免其早期恶化转移,可尽早手术切除。腹腔镜手术是治疗囊性神经母细胞瘤安全有效的方法。
- Abstract:
- ObjectiveTo explore the diagnosis and treatment of cystic neuroblastoma in children and examine the safety and efficacy of laparoscopic resection.MethodsFrom June 2016 to December 2021,6 CNB children underwent laparoscopic resection.The relevant clinical data were collected and long-term postoperative complications observed.ResultsThere were 4 boys and 2 girls.Abdominal cystic mass was detected by prenatal ultrasonography.Five of them underwent laparoscopic resection successfully while one was converted into open surgery.Mean operative age was 12(8-38) days,mean operative duration 87(60-120) min and mean volume of blood loss 5.6(1-10) ml.Blood transfusion was not required.Mean postoperative hospital stay was 9.5(7-11) days.Cystic neuroblastoma was confirmed by postoperative pathological examination.None of them received chemotherapy.No recurrence was noted during a follow-up period of (6-71) months.ConclusionWith benign biological features,CNB has a decent prognosis.However,it should be operated as early as possible to prevent metastasis and other risks.Laparoscopic surgical resection is both safe and efficacious for cystic neuroblastoma.
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备注/Memo
收稿日期:2022-08-20。
基金项目:湖北省第二届医学领军人才工程培养对象暨湖北名医工作室(鄂卫通2019—47号)
通讯作者:杨星海,Email:75493654@qq.com