Chen Xiaoqing,Zhu Libin.Recent advances of clinical application of near infrared spectroscopy technology for pediatric intestinal diseases[J].Journal of Clinical Pediatric Surgery,2022,21(10):991-994.[doi:10.3760/cma.j.cn101785-202111025-016]
近红外光谱技术在儿童肠道疾病诊治中的应用进展
- Title:
- Recent advances of clinical application of near infrared spectroscopy technology for pediatric intestinal diseases
- Keywords:
- Spectroscopy; Near-Infrared; Diagnosis; Intestines; Pathology; Enterocolitis; Necrotizing; Colitis
- 摘要:
- 肠道疾病是儿童常见疾病之一,儿童肠道疾病多因临床表现不典型、患儿表达不清楚而难以早期明确诊断,如发生肠道缺血缺氧性疾病,需尽早明确诊断并予以治疗。近红外光谱(near infrared spectroscopy,NIRS)技术是一种无创光学成像技术,它通过近红外光测量组织中氧合和脱氧血红蛋白的浓度变化,来间接评估肠道血流动力学变化。近年来,NIRS技术在监测局部组织氧合、体现局部组织活力和鉴别良恶性肿瘤及检测生物标志物等方面得到了较好的应用,可以起到预判肠道疾病的发生发展、评估肠道疾病预后、改善治疗效果等作用。本文就NIRS技术在儿童肠道疾病中的应用进展进行综述。
- Abstract:
- Intestinal diseases are one of the most common diseases in children.Due to atypical clinical manifestations and indistinct oral expressions in young children,the diagnosis of pediatric intestine is mostly delayed while intestinal ischemia and hypoxia occur frequently as a clinical emergency.Near infrared spectroscopy (NIRS) is a noninvasive optical imaging tool of indirectly assessing intestinal hemodynamics through near-infrared light for measuring the concentration changes of oxyhemoglobin and deoxyhemoglobin in tissues.In recent years,NIRS technology has made great headways in monitoring local tissue oxygenation situation,reflecting local tissue vitality,identifying benign and malignant tumors and detecting biomarkers.It can play some roles in predicting the occurrence and severity of intestinal diseases,improving the therapeutic effect of diseases and assessing the prognosis of intestinal diseases.This review focused upon clinical applications of NIRS technology for pediatric surgical intestinal diseases.
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备注/Memo
收稿日期:2021-11-13。
基金项目:浙江省医药卫生项目(2021PY014);浙江省基础公益研究计划项目(LGF21H040009);温州市社会发展(医疗卫生)科技项目(ZY2021027)
通讯作者:朱利斌,Email:zhulibin@wmu.edu.cn