Liu Wenying.Classifications and clinical managements of vascular abnormalities[J].Journal of Clinical Pediatric Surgery,2019,18(08):621-625.[doi:10.3969/j.issn.1671-6353.2019.08.001]
脉管异常类疾病的分类及相关临床问题
- Title:
- Classifications and clinical managements of vascular abnormalities
- Keywords:
- Hemangioma; Vascular Malformations; Iymphatic Malformations; Child
- 分类号:
- R732.2
- 摘要:
- 脉管异常类疾病是一组以血管和淋巴管病变为主的疾病,多发生于儿童。不同类型脉管异常类疾病具有各自的病理生理及临床特征。准确合适的分类有利于临床决策和预后的改善。目前对脉管异常类疾病的发病机制尚不十分清楚,新的分类越来越细,治疗理念和技术也不断更新,而临床诊疗上仍然存在治疗时机、指征、治疗方法等不明确或有争议的现象,亟待进一步完善与规范。本文旨在阐述脉管异常类疾病的分类及相关临床问题。
- Abstract:
- Vascular abnormalities are a diverse group of vascular and lymphatic diseases occurring frequently in children.Different clinical types have their unique pathophysiological characteristics so that classifying accurately and treating properly are essential.Considering that the etiology and mechanism of these diseases have not been fully elucidated and new methods and technologies are emerging continuously,the standardization of vascular abnormalities has become more imperative.This paper summarizes the classifications,growth characteristics,diagnostics,treatment options and current dilemmas of vascular anomalies.
参考文献/References:
1 Esposito F,Ferrara D,Di Serafino MA,et al.Classification and ultrasound findings of vascular anomalies in pediatric age:the essential[J].J Ultrasound,2019,22(1):13-25.DOI:10.1007/s40477-018-0342-1.
2 Mulliken JB,Glowacki J.Hemangiomas and vascular malformations in infants and children:a classification based on endothelial characteristics[J].Plast Reconstr Surg,1982,69(3):412-422.
3 Taghinia AH,Upton J.Vascular anomalies[J].J Hand Surg Am,2018,43(12):1113-1121.DOI:10.1016/j.jhsa.2018.03.046.
4 Jackson IT,Carreño R,Potparic Z,et al.Hemangiomas,vascular malformations,and lymphovenous malformations:classification and methods of treatment[J].Plast Reconstr Surg,1993,91(7):1216-1230.
5 Waner M,Suen JY.Management of congenital vascular lesions of the head and neck[J].Oncology (Williston Park),1995,9(10):989-994.
6 Powell J.Update on hemangiomas and vascular malformations[J].Curr Opin Pediatr,1999,11(5):457-463.
7 Dasgupta R,Fishman SJ.ISSVA classification[J].Semin Pediatr Surg,2014,23(4):158-161.DOI:10.1053/j.sempedsurg.2014.06.016.
8 International society for the study of vascular anomalies.ISSVA classification for Vascular Anomalies[EB/OL] [2019-08-06].http://www.issva.org/UserFiles/file/ISSVA-Classification-2018.pdf.
9 Sandbank S,Molho-Pessach V,Farkas A,et al.Oral and topical sirolimus for vascular anomalies:a multicentre study and review[J],2019.DOI:10.2340/00015555-3262.[Epub ahead of print]
10 Léauté-Labrèze C,Harper JI,Hoeger PH.Infantile haemangioma[J].Lancet,2017,390 (10089):85-94.DOI:10.1016/S0140-6736(16)00645-0.
11 Gupta A,Verma A,Dhua A,et al.Vascular anomalies:a pediatric surgeon’s perspective[J].Indian J Pediatr,2017,84(8):612-617.DOI:10.1007/s12098-017-2355-8.
12 Orlow SJ,Isakoff MS,Blei F.Increased risk of symptomatic hemangiomas of the airway in association with cutaneous hemangiomas in a "beard" distribution[J].J Pediatr,1997,131(4):643-646.
13 Bota M,Popa G,Blag C,et al.Infantile hemangioma:a brief review[J].Clujul medical,2015,88(1):23-27.DOI:10.15386/cjmed-381.
14 Léauté-Labrèze C,Dumas De La Roque E,Hubiche T,et al.Propranolol for severe hemangiomas of infancy[J].N Engl J Med,2008,358(24):2649-2651.DOI:10.1056/NEJMc0708819.
15 Nassiri N,Thomas J,Cirillo-Penn NC.Evaluation and management of peripheral venous and lymphatic malformations[J].J Vasc Surg Venous Lymphat Disord,2016,4(2):257-265.DOI:10.1016/j.jvsv.2015.09.001.
16 Kennedy TL,Whitaker M,Pellitteri P,et al.Cystic hygroma/lymphangioma:A rational approach to management[J].Laryngoscope,2001,111(11,pt 1):1929-1937.DOI:10.1097/00005537-200111000-00011.
17 Coffin CM,Dehner LP.Vascular tumors in children and adolescents:a clinicopathologic study of 228 tumors in 222 patients[J].Pathol Annu,1993,28 Pt 1:97-120.
18 Swetman GL,Berk DR,Vasanawala SS,et al.Sildenafil for severe lymphatic malformations[J].N Engl J Med,2012,366(4):384-386.DOI:10.1056/NEJMc1112482.
19 Leaute-Labreze C,Hoeger P,Mazereeuw-Hautier J,et al.A randomized,controlled trial of oral propranolol in infantile hemangioma[J].N Engl J Med,2015,372(8):735-746.DOI:10.1056/NEJMoa1404710.
20 Siegfried EC,Keenan WJ,Al-Jureidini S.More on propranolol for hemangiomas of infancy[J].N Engl J Med,2008,359(26):2846.DOI:10.1056/NEJMc086443.
21 Legiehn GM,Heran MK.Venous malformations:Classification,development,diagnosis,and interventional radiologic management[J].Radiol Clin North Am,2008,46(3):545.DOI:10.1016/j.rcl.2008.02.008.DOI:10.1016/j.rcl.2008.02.008.
22 Richter GT,Braswell L.Management of venous malformations[J].Facial Plast Surg,2012,28(6):603-610.
相似文献/References:
[1]周启星,杨文,成琦,等.婴儿腮腺血管瘤22例[J].临床小儿外科杂志,2007,6(03):17.
[2]杨恩 刘铭 彭强. 血管瘤血管内皮生长因子受体KDR基因异常甲基化的研究[J].临床小儿外科杂志,2012,11(04):268.
[J].Journal of Clinical Pediatric Surgery,2012,11(08):268.
[3]徐仙赟 谢琼珺 黄海金. 噻吗洛尔和普萘洛尔体外调控小鼠血管瘤细胞增殖及凋亡作用的比较[J].临床小儿外科杂志,2014,13(02):117.
[4]黄文雅 肖 天 李春旺 邓 敏 金 科.血管瘤并血小板减少综合征介入栓塞治疗的效果分析[J].临床小儿外科杂志,2018,17(01):43.
Huang Wenya,Xiao Tian,Li Chunwang,et al.Interventional treatment for KasabachMerrit syndrome in children:a report of 7 cases.[J].Journal of Clinical Pediatric Surgery,2018,17(08):43.
[5]高石,赵国强,岳晓洁.儿童指端血管球瘤1例报道并文献复习[J].临床小儿外科杂志,2019,18(07):615.[doi:10.3969/j.issn.1671-6353.2019.07.019]
Gao Shi,Zhao Guoqiang,Yue Xiaojie.A case report of a fingertip glomus tumor in children and literature review[J].Journal of Clinical Pediatric Surgery,2019,18(08):615.[doi:10.3969/j.issn.1671-6353.2019.07.019]
[6]王川,李亚楠,向波,等.婴幼儿血管瘤生活质量专用量表的信度与效度检验及其临床应用[J].临床小儿外科杂志,2019,18(08):635.[doi:10.3969/j.issn.1671-6353.2019.08.004]
Wang Chuan,Li Yanan,Xiang Bo,et al.Measuring reliability and validity of a Chinese mandarin version quality-of-life instrument for infantile hemangioma and its clinical application[J].Journal of Clinical Pediatric Surgery,2019,18(08):635.[doi:10.3969/j.issn.1671-6353.2019.08.004]
[7]张明,彭强,刘铭.NF-κB因子在普萘洛尔治疗裸鼠血管瘤模型过程中的表达[J].临床小儿外科杂志,2019,18(08):655.[doi:10.3969/j.issn.1671-6353.2019.08.008]
Zhang Ming,Peng Qiang,Liu Ming.Expression of NF-kappa B in propranolol treatment for infantile hemangioma in nude mice model[J].Journal of Clinical Pediatric Surgery,2019,18(08):655.[doi:10.3969/j.issn.1671-6353.2019.08.008]
[8]树叶,黄文雅,罗勇奇,等.10例婴幼儿卡梅综合征临床特征及治疗经验总结[J].临床小儿外科杂志,2019,18(09):775.[doi:10.3969/j.issn.1671-6353.2019.09.014]
Shu Ye,Huang Wenya,Luo Yongqi,et al.Summary of clinical features and treatment protocols of 10 infants with Kasabach-Merritt syndrome[J].Journal of Clinical Pediatric Surgery,2019,18(08):775.[doi:10.3969/j.issn.1671-6353.2019.09.014]
[9]王长凤,孙佳丽,吴长华,等.595 nm脉冲染料激光联合噻吗洛尔滴眼液治疗浅表性婴幼儿血管瘤的疗效观察[J].临床小儿外科杂志,2019,18(11):953.[doi:10.3969/j.issn.1671—6353.2019.11.011]
Wang Changfeng,Sun Jiali,Wu Changhua,et al.Curative efficacy of timolol plus 595nm pulsed dye laser for superficial infantile hemangioma[J].Journal of Clinical Pediatric Surgery,2019,18(08):953.[doi:10.3969/j.issn.1671—6353.2019.11.011]
[10]王怀杰,谢崇,蔺卫龙,等.纤维脂肪血管病变13例的诊断与治疗[J].临床小儿外科杂志,2022,21(07):668.[doi:10.3760/cma.j.cn101785-202102022-014]
Wang Huaijie,Xie Chong,Lin Weilong,et al.Diagnosis and treatment of fibro-adipose vascular anomaly(FAVA)[J].Journal of Clinical Pediatric Surgery,2022,21(08):668.[doi:10.3760/cma.j.cn101785-202102022-014]
备注/Memo
收稿日期:2019-07-19。
基金项目:国家自然科学基金(编号:81401606);四川大学优秀青年学者基金(编号:2015SU04A15)