Wen Jianguo.From symptoms to function:transformation and reflections on urodynamic study-driven personalized treatment of lower urinary tract symptoms in children[J].Journal of Clinical Pediatric Surgery,2026,(07):601-605.[doi:10.3760/cma.j.cn101785-20260507-00218]
从症状到功能:尿动力检查推动儿童下尿路症状个体化治疗的变革与思考
- Title:
- From symptoms to function:transformation and reflections on urodynamic study-driven personalized treatment of lower urinary tract symptoms in children
- Keywords:
- Child; Lower Urinary Tract Symptom; Urodynamic Study; Individualized Treatment; Detrusor Overactivity; Posterior Urethral Valve; Transcutaneous Electrical Nerve Stimulation
- 摘要:
- 儿童下尿路症状(lower urinary tract symptoms,LUTS)病因复杂、表型异质性强,常规症状学评估难以精准分型,易导致治疗同质化与疗效不佳。尿动力检查(urodynamic study,UDS)作为评估儿童膀胱尿道功能的核心技术,可客观量化逼尿肌功能、尿道闭合状态及储排尿协同性,为LUTS分型诊断、风险分层及个体化方案制定提供关键依据。本文系统梳理儿童UDS技术进展与临床应用现状,整合国内多家儿童医院相关研究成果,重点评述UDS指导下LUTS个体化治疗的核心策略、疗效优势及现存争议,分析当前UDS临床推广的瓶颈与挑战,结合各研究不足提出针对性未来研究方向,为提升儿童LUTS诊疗精准化水平提供参考。
- Abstract:
- Lower urinary tract symptoms (LUTS) in children have complex etiologies and highly heterogeneous phenotypes.Conventional symptom-based assessment is often insufficient for precise classification,which may lead to homogenized treatment and unsatisfactory outcomes.Urodynamic study (UDS),as a core technique for evaluating bladder and urethral function in children,can objectively quantify detrusor function,urethral closure status,and storage-voiding coordination,thereby providing key evidence for phenotypic diagnosis,risk stratification,and individualized treatment planning of LUTS.This article systematically reviews advances in pediatric UDS technology and its current clinical applications,integrates relevant research findings from multiple children’s hospitals in China,and focuses on the core strategies,therapeutic advantages,and existing controversies of UDS-guided personalized treatment for LUTS.It also analyzes the current bottlenecks and challenges in the clinical implementation of UDS and proposes targeted future research directions based on the limitations of existing studies,aiming to provide reference for improving the precision of diagnosis and treatment of pediatric LUTS.
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备注/Memo
收稿日期:2026-5-7。
基金项目:国家自然科学基金(82470807)
通讯作者:文建国,Email:jgwen@zzu.edu.cn