Xu Chencheng,Jiang Dapeng.Donor factors for kidney transplantation in children[J].Journal of Clinical Pediatric Surgery,2022,21(05):410-414.[doi:10.3760/cma.j.cn101785-202111027-003]
儿童肾脏移植中需要关注的供体因素
- Title:
- Donor factors for kidney transplantation in children
- 摘要:
- 肾脏移植是终末期肾病(end-stage renal disease,ESRD)的最佳治疗方案。活体供肾的长期存活率更高,对ESRD患儿来说是一个更好的选择。不同供体因素,如供肾来源(活体/尸体器官)、供肾大小、人类白细胞抗原(human leukocyte antigen,HLA)相容性、供体年龄等因素都可能影响肾移植的长期预后,对于儿童患者,需要着重考虑供肾的长期存活率,尽可能降低移植风险。本文就儿童肾脏移植中需要关注的供体因素进行综述。
- Abstract:
- Kidney transplantation is an optimal treatment for children with end-stage renal disease (ESRD). There is a great diversity of donor factors, such as source of donor kidney (living/dead organ), size of donor kidney, infection of donor source, compatibility of human leukocyte antigen (HLA) and donor age, etc. The long-term prognosis of transplantation is affected. For children, it is necessary to focus upon long-term survival rate and minimize the risk of transplantation. Therefore careful consideration should be given when selecting different transplant donors. A large gap between organ supply and demand has been an ongoing global challenge. It is im- perative to further the refine techniques of organ preservation and boost public awareness of organ donation.
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备注/Memo
收稿日期:2021-11-16。
基金项目:上海市自然科学基金（19ZR1432800）
通讯作者:姜大朋,Email:jdp509@163.com