PDF下载

[1]廖文戈,彭强,任清华,等.精准肝脏外科理念在儿童肝母细胞瘤中的应用进展[J].临床小儿外科杂志,2021,20(11):1082-1085.[doi:10.12260/lcxewkzz.2021.11.016]
　Liao Wenge,Peng Qiang,Ren Qinghua,et al.Application advances of precision liver surgery for pediatric hepatoblastoma[J].Journal of Clinical Pediatric Surgery,2021,20(11):1082-1085.[doi:10.12260/lcxewkzz.2021.11.016]

点击复制

精准肝脏外科理念在儿童肝母细胞瘤中的应用进展

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 第20卷期数: 2021年11期页码: 1082-1085 栏目: 综述出版日期: 2021-11-20

Title:: Application advances of precision liver surgery for pediatric hepatoblastoma

作者:: 廖文戈¹; 彭强¹; 任清华²; 王焕民²; 1. 中国电子科技大学医学院附属成都妇女儿童中心医院儿外科(四川省成都市, 610000);
2. 首都医科大学附属北京儿童医院肿瘤外科(北京市, 100045)

Author(s):: Liao Wenge¹; Peng Qiang¹; Ren Qinghua²; Wang Huanmin²; 1. Department of Pediatric Surgery, Chengdu Women&Children’s Central Hospital, School of Medicine, University of Electronic Science & Technology of China, Chengdu 610000, China;
2. Department of Surgical Oncology, Beijing Children’s Hospital, Capital M

关键词:: 肝肿瘤/外科学; 肝肿瘤/治疗; 肝切除术; 儿童

Keywords:: Liver Neoplasms/SU; Liver Neoplasms/TH; Hepatectomy; Child

分类号:: R735.7;R726.1

DOI:: 10.12260/lcxewkzz.2021.11.016

摘要:: 肝母细胞瘤（hepatoblastoma，HB）是儿童期常见的肝脏恶性实体肿瘤。伴随精准肝脏外科理念的引入及发展，儿童肝母细胞瘤的手术治疗借助现代信息技术平台，已跨入精准肝切除时代。本文从儿童肝母细胞瘤精准肝脏外科理念的理论基础，解剖基础、技术支撑、术前评估以及手术进展进行综述。

Abstract:: Hepatoblastoma (HB) is the most common malignant solid hepatic tumor in children. With the introduction and development of the concept of precise surgery, surgical treatment of pediatric hepatoblastoma has marched into the era of precise hepatic resection with an aid of modern information and technology platforms. Here anatomical basis, technical supports, preoperative evaluations and surgical advances of pediatric hepatoblastoma are reviewed.

参考文献/References:

1 Hiyama E, Hishiki T, Watanabe K, et al. Mortality and morbidity in primarily resected hepatoblastomas in Japan:Experience of the JPLT (Japanese Study Group for Pediatric Liver Tumor) trials[J].J Pediatr Surg, 2015, 50(12):2098-2101.DOI:10.1016/j.jpedsurg.2015.08.035.
2 Kortekaas M, Bartelink M, Zuithoff N, et al. Does integrated training in evidence-based medicine (EBM) in the general practice (GP) specialty training improve EBM behaviour in daily clinical practice? A cluster randomised controlled trial[J].BMJOPEN, 2016, 6:1-12.DOI:10.1136/bmjopen-2015-010537.
3 段伟东, 董家鸿.精准外科理念的哲学思考[J].医学与哲学, 2016, 37(8):19-22.DOI:10.12014/j.issn.1002-0772.2016.08a.04. Duan WD, Dong JH.Philosophic thought of precision surgery[J].Medicine and Philosophy, 2016, 37(8):19-22.DOI:10.12014/j.issn.1002-0772.2016.08a.04.
4 杜锡林, 杨涛, 陈安, 等. 肝血流阻断技术在肝切除术中的应用评述[J].西部医学, 2015, 27(7):961-963, 970.DOI:10.3969/j.issn.1672-3511.2015.07.001. Du XL, Yang T, Chen A, et al. Application of hepatic vascular exclusion techniques for liver resection[J].Med J West China, 2015, 27(7):961-963, 970.DOI:10.3969/j.issn.1672-3511.2015.07.001.
5 中华医学会外科学分会胆道外科学组, 中国医师协会外科医师分会胆道外科学.围肝门区域外科技术临床应用路径中国专家共识(2020版)[J].中国实用外科杂志, 2020, 40(6):626-633.DOI:10.19538/j.cjps.issn1005-2208.2020.06.02. Chinese Society of Biliary Tract Surgery, Chinese Society of Surgery, Chinese Medical Association;Biliary Tract Professional Committee in Surgery, Chinese College of Surgeons, Chinese Medical Doctor Association:Chinese Expert Consensus on Clinical Application Path of Perihilar Surgical Technique (2020 Edition)[J].Chinese Journal of Practical Surgery, 2020, 40(6):626-633.DOI:10.19538/j.cjps.issn1005-2208.2020.06.02.
6 Kim JH, Kim H.Pure laparoscopic anatomical segment v resection using the extrafascial and transfissural glissonean approach[J].Annals of Surgical Oncology, 2019, 26(7):2241.DOI:10.1245/s10434-019-07324-9.
7 李斌, 姜小清.重视门短静脉解剖在围肝中的意义[J].中国实用外科杂志, 2019, 39(2):145-148.DOI:10.19538/j.cjps.issn1005-2208.2019.02.11. Li B, Jiang XQ.Stressing the significance of "short hepatic portal vein" anatomy during perihepatic portal surgery[J].Chinese Journal of Practical Surgery, 2019, 39(2):145-148.DOI:10.19538/j.cjps.issn1005-2208.2019.02.11.
8 Nayyer I, Kamal H, Vinita S, et al. Red blood cell transfusion and outcome in cancer[J].Transfus Apher Sci, 2017, 56(3):287-290.DOI:10.1016/j.transci.2017.05.014.
9 Zhang XL, Wang WJ, Cao N, et al. Effectiveness and safety of controlled venous pressure in liver surgery:a systematic review and network Meta-Analysis[J].BioMed Research International, 2015, 20(12):1-10.DOI:10.1155/2015/290234.
10 Meyers RL, Maibach R, Hiyama E, et al. Risk-stratified staging in paediatric hepatoblastoma:a unified analysis from the Childrens Hepatic tumors International Collaboration[J].Lancet Oncol, 2017, 18(1):122-131.DOI:10.1016/S1470-2045(16)30598-8.
11 Towbin AJ, Meyers RL, Woodley H, et al. 2017 PRETEXT:radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT)[J].Pediatr Radiol, 2018, 48(4):536-554.DOI:10.1007/s00247-018-4078-z.
12 倪鑫, 马晓莉, 王焕民, 等. 儿童肝母细胞瘤诊疗规范(2019年版)[J].临床肝胆病杂志, 2019, 35(11):2431-2434.DOI:10.3969/j.issn.1001-5256.2019.11.008. Ni X, Ma XL, Wang HM, et al. Guidelines for Diagnosing and Treating Pediatric Hepatoblastoma (2019 Edition)[J].J Clin Hepatol, 2019, 35(11):2431-2434.DOI:10.3969/j.issn.1001-5256.2019.11.008.
13 Nanashima A, Abo T, Arai J, et al. Comprehensive predictors of portal pressure from functional liver reserve in patients who underwent hepatectomy[J].Indian J Surg, 2015, 77(S3):923-929.DOI:10.1007/s12262-014-1065-y.
14 袁妙贤, 尹强, 刘朝阳.肝脏中叶切除术治疗小儿肝脏肿瘤疗效与安全性分析[J].临床小儿外科杂志, 2019, 18(10):859-863.DOI:10.3969/j.issn.1671-6353.2019.10.012. Yuan MX, Yin Q, Liu CY.Efficacy and safety of mesohepatectomy in the treatment of hepatic tumors in children[J].J Clin Ped Sur, 2019, 18(10):859-863.DOI:10.3969/j.issn.1671-6353.2019.10.012.
15 姚伟, 董岿然, 李凯, 等. 吲哚菁绿荧光显像技术在肝母细胞瘤精准切除手术中的应用[J].临床小儿外科杂志, 2019, 18(2):107-111.DOI:10.3969/j.issn.1671-6353.2019.02.008. Yao W, Dong KR, Li K, et al. Application of indocyanine green fluorescent imaging technique in precise hepatectomy for hepatoblastoma[J].J Clin Ped Sur, 2019, 18(2):107-111.DOI:10.3969/j.issn.1671-6353.2019.02.008.
16 杨维, 任清华, 秦红, 等. 儿童肝母细胞瘤精准肝切除手术效果评价[J].临床小儿外科杂志, 2020, 19(5):392-397.DOI:10.3969/j.issn.1671-6353.2020.05.004. Yang W, Ren QH, Qin H, et al. Outcome evaluations of precision liver resection for pediatric hepatoblastoma[J].J Clin Ped Sur, 2020, 19(5):392-397.DOI:10.3969/j.issn.1671-6353.2020.05.004.
17 Kueht M, Thompson P, Rana A, et al. Effects of an early referral system on liver transplantation for hepatoblastoma at Texas Children’s Hospital[J].Pediatr Transplant, 2016, 20(4):515-522.DOI:10.1111/petr.12699.
18 Nota CLMA, Molenaar IQ, Borel Rinkes IHM, et al. Robotic right hepatectomy for a central liver tumor-A video of the surgical technique[J].Surg Oncol, 2019, 30:108.DOI:10.1016/j.suronc.2019.06.009.

相似文献/References:

[1]王俊,蔡威,张驰,等.新生儿肝母细胞瘤诊2例治分析[J].临床小儿外科杂志,2008,7(05):1.
[2]杨振宇,陈福真,李滨,等.小儿亲体部分肝移植治疗肝母细胞瘤(附1例报告)[J].临床小儿外科杂志,2007,6(02):12.
[3]王焕民秦红祝秀丹常晓峰杨维. 小儿肝门部肝母细胞瘤的手术策略[J].临床小儿外科杂志,2011,10(05):323.
　[J].Journal of Clinical Pediatric Surgery,2011,10(11):323.
[4]董岿然.联合肝脏离断和门静脉结扎二步肝切除术在儿童肝肿瘤治疗中的应用[J].临床小儿外科杂志,2020,19(05):382.[doi:10.3969/j.issn.1671-6353.2020.05.002]
　Dong Kuiran.Application of associated liver partition and portal vein ligation for staged hepatectomy in the treatment of liver tumors in children[J].Journal of Clinical Pediatric Surgery,2020,19(11):382.[doi:10.3969/j.issn.1671-6353.2020.05.002]
[5]冯俊,王焕民,秦红,等.儿童肝母细胞瘤手术后胆瘘的诊断与治疗分析[J].临床小儿外科杂志,2020,19(09):794.[doi:10.3969/j.issn.1671-6353.2020.09.007]
　Feng Jun,Wang Huanmin,Qin Hong,et al.Diagnosis and treatment of postoperative biliary fistula in children with hepatoblastoma[J].Journal of Clinical Pediatric Surgery,2020,19(11):794.[doi:10.3969/j.issn.1671-6353.2020.09.007]
[6]彭宇明,尹强,盛新仪,等.3D腹腔镜下前入路经肝正中裂劈开儿童肝尾状叶肿瘤切除术[J].临床小儿外科杂志,2020,19(11):1007.[doi:10.3969/j.issn.1671-6353.2020.11.009]
　Peng Yuming,Yin Qiang,Sheng Xinyi,et al.Three-dimensional laparoscopic resection of caudate lobe hepatic tumor via an anterior approach in children[J].Journal of Clinical Pediatric Surgery,2020,19(11):1007.[doi:10.3969/j.issn.1671-6353.2020.11.009]
[7]谭钦,张明满.儿童肝母细胞瘤预后相关因素的研究进展[J].临床小儿外科杂志,2021,20(05):474.[doi:10.12260/lcxewkzz.2021.05.015]
　Tan Qin,Zhang Mingman.Research progress on prognostic factors of hepatoblastoma in children[J].Journal of Clinical Pediatric Surgery,2021,20(11):474.[doi:10.12260/lcxewkzz.2021.05.015]
[8]施佳,程千千,武志祥,等.吲哚菁绿近红外荧光显像在儿童肝母细胞瘤手术中的应用初探[J].临床小儿外科杂志,2021,20(10):916.[doi:10.12260/lcxewkzz.2021.10.004]
　Shi Jia,Cheng Qianqian,Wu Zhixiang,et al.Application of near-infrared Indocyanine Green fluorescence imaging in the Surgery of Childhood Hepatoblastoma[J].Journal of Clinical Pediatric Surgery,2021,20(11):916.[doi:10.12260/lcxewkzz.2021.10.004]
[9]刘金桥,陈文娟,尹强,等.数字化三维重建技术联合术中B超导航在儿童解剖性肝切除手术中的应用研究[J].临床小儿外科杂志,2021,20(10):930.[doi:10.12260/lcxewkzz.2021.10.007]
　Liu Jinqiao,Chen Wenjuan,Yin Qiang,et al.Application of digital three-dimensional reconstruction technology combined with intraoperative B-ultrasound navigation in children’s anatomical liver resection[J].Journal of Clinical Pediatric Surgery,2021,20(11):930.[doi:10.12260/lcxewkzz.2021.10.007]
[10]俞星雨,顾松,李云洁,等.肝母细胞瘤Wnt/β-catenin信号通路研究进展[J].临床小儿外科杂志,2022,21(07):688.[doi:10.3760/cma.j.cn101785-202107049-018]
　Yu Xingyu,Gu Song,Li Yunjie,et al.Recent advance of Wnt/β-catenin signaling pathway in hepatoblastoma[J].Journal of Clinical Pediatric Surgery,2022,21(11):688.[doi:10.3760/cma.j.cn101785-202107049-018]

备注/Memo

收稿日期:2021-02-05。
基金项目:四川省医学会专项科研项目（编号：2019SAT19）
通讯作者:王焕民,Email:wanghuanmin@bch.com.cn

更新日期/Last Update: 1900-01-01