[1]沈志鹏,张文博,石武杰,等.经幕下小脑上入路切除儿童松果体区肿瘤的临床效果分析[J].临床小儿外科杂志,2021,20(05):420-424.[doi:10.12260/lcxewkzz.2021.05.005]
　Shen Zhipeng,Zhang Wenbo,Shi Wujie,et al.Clinical efficacy of infratentorial supracerebellar approach for resecting pineal tumors in children[J].Journal of Clinical Pediatric Surgery,2021,20(05):420-424.[doi:10.12260/lcxewkzz.2021.05.005]
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经幕下小脑上入路切除儿童松果体区肿瘤的临床效果分析

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 第20卷 期数: 2021年05期 页码: 420-424 栏目: 专题·儿童脑肿瘤的诊治 出版日期: 2021-05-25
Title:
Clinical efficacy of infratentorial supracerebellar approach for resecting pineal tumors in children
作者:
沈志鹏;  张文博;  石武杰;  翁建彬;  章培良;  林超;  王宁
浙江大学医学院附属儿童医院神经外科, 国家区域性儿童医疗中心(浙江省杭州市, 310052)
Author(s):
Shen Zhipeng;  Zhang Wenbo;  Shi Wujie;  Weng Jianbin;  Zhang Peiliang;  Lin Chao;  Wang Ning
Department of Neurosurgery, Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China
关键词:
松果体瘤/外科学; 治疗结果; 儿童
Keywords:
Pinealoma/SU; Treatment Outcome; Child
分类号:
R739.4;R726.1
DOI:
10.12260/lcxewkzz.2021.05.005
摘要:
目的 探讨经幕下小脑上入路手术治疗儿童松果体区肿瘤的效果，并分析其临床预后。方法 以浙江大学医学院附属儿童医院2015年1月至2020年1月神经外科收治的35例在解剖学特征上适合接受经幕下小脑上入路手术治疗的儿童松果体区肿瘤患者（年龄≤18岁）作为研究对象，根据患者的基线数据和术后生存情况对该术式的临床疗效进行分析。结果 35例中纯生殖细胞瘤13例，畸胎瘤10例，松果体母细胞瘤6例，混合性肿瘤2例，非典型畸胎样/横纹肌样肉瘤2例，星型细胞瘤1例，内胚窦瘤1例。肿瘤全切28例（80.0%），次全切5例（14.3%），活检2例（5.7%）。随访过程中4例死亡（11.4%），2例术后复发（5.7%）。结论 儿童松果体区肿瘤以生殖细胞瘤和畸胎瘤多见，经幕下小脑上入路手术切除有较高的全切率，且大多数患者具有较高的长期生存率。
Abstract:
Objective To explore the surgical efficacy and outcomes of infratentorial supracerebellar approach for pineal tumors in children.Methods From January 2015 to January 2020,a total of 35 children aged under ≤ 18 years with pineal tumors anatomically suitable for infratentorial supracerebellar approach were enrolled.Retrospective analysis was performed for baseline data and postoperative survival.Results There were pure germinomas (n=13),teratomas (n=10),pinealblastoma (n=6),mixed tumors (n=2),atypical teratoid/rhabdoid tumor (n=2),astrocytoma (n=1) and yolk sac tumor (n=1).And the procedures included total tumor resection (n=28,80%),subtotal resection (n=5,14.3%) and biopsy (n=2,5.7%).By the end of follow-ups,there were death (n=4,11.4%) and postoperative recurrence (n=2,5.7%).Conclusion Most cases of pediatric pineal tumors are germinomas and teratomas.And infratentorial supracerebellar approach has a high resection rate and a high long-term survival rate.

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备注/Memo

收稿日期:2021-01-16。
基金项目:浙江省医药卫生科技计划项目（编号：JSW2013-A017）
作者简介:沈志鹏,Email:shenzp@zju.edu.cn

更新日期/Last Update: 1900-01-01