Mao Jianxiong,Li Suyi,Luo Yan,et al.Etiological analysis and clinical medication of acute appendicitis in children.[J].Journal of Clinical Pediatric Surgery,2018,17(04):278-281.
儿童急性阑尾炎的病原学分析与临床用药探讨
- Title:
- Etiological analysis and clinical medication of acute appendicitis in children.
- Keywords:
- Child; Acute appendicitis; Etiology; Susceptibility Testing
- 文献标志码:
- A
- 摘要:
-
目的 分析儿童急性阑尾炎的常见致病菌及药敏试验结果，探讨儿童急性阑尾炎的临床
用药方法。 方法 选择本院收治的４０６例急性阑尾炎患儿的腹腔脓液做细菌培养及药敏试验，统计
细菌培养及药敏试验结果，总结儿童阑尾炎常见的病原菌及对儿科常用药物的敏感性。 结果 ４０６
例患儿中，１１８例（占２９．１％）无细菌生长，１９５例（占４８．０％）为大肠埃希菌，３８例（占９．４％）为大肠埃
希菌及铜绿假单胞菌，１１例（占２．７％）为大肠埃希菌及肺炎克雷伯菌，９例（占２．２％）为肺炎克雷伯
菌，其它细菌占８．６％。在培养所得的大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌的三种病原菌中，氨苄
西林的耐药性分别为８４．２％、９５％、１００％；哌拉西林的耐药性分别为０％、０％、１１．１％；头孢吡肟的耐药
率分别为２７．２％、０％、２２．２％；头孢曲松的耐药性分别为４８．２％、１００％、３３．３％；头孢他啶的耐药性分
别为３４．２％、０％、２２．２％；氨曲南的耐药性分别为３５．９％、０％、２２．２％；亚胺培南的耐药性分别为０％、
０％、０％。 结论 大肠埃希菌是阑尾炎的主要致病菌，它对大多数抗生素都产生了耐药。铜绿假单胞
菌对抗生素选择性耐药，肺炎克雷伯菌对大多数抗生素都敏感。
- Abstract:
- ObjectiveTo explore the common pathogens and antimicrobial susceptibility test results for acute appendicitis to guide rational use of drugs in children.MethodsFor 406 cases of acute appendicitis in children with celiac pus,bacterial culture and sensitivity test were performed for identifying common pathogens and determining sensitivity of common pediatric drugs.ResultsAmong them,118 cases (29.1%) showed no bacterial growth,195 (48.0%) Escherichia coli,38 (9.4%) Escherichia coli and Pseudomonas aeruginosa,11 (2.7%) Escherichia coli and Klebsiella pneumoniae,9 (2.2%) Klebsiella pneumoniae and (8.6%) other bacteria.For Escherichia coli,Pseudomonas aeruginosa and Klebsiella pneumoniae,the rates of ampicillin resistance were 84.2%,95% and 100%;piperacillin 0%,0%,11.1%;cefepime 27.2%,0%,22.2%;ceftriaxone48.2%,100%,33.3%;ceftazidime 34.2%,0%,22.2%;aztreonam 35.9%,0%,22.2%;imipenem 0%,0%,0% .ConclusionAs a major pathogen of appendicitis,Escherichia coli is resistant to most antibiotics.Pseudomonas aeruginosa is resistant while Klebsiella pneumoniae remains sensitive to most antibiotics.
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