Li Yaqin,Li Lun,Xu Taotao,et al.Research advances of subacute osteomyelitis in children[J].Journal of Clinical Pediatric Surgery,2023,22(05):485-489.[doi:10.3760/cma.j.cn101785-202211063-016]
儿童亚急性骨髓炎的研究进展
- Title:
- Research advances of subacute osteomyelitis in children
- Keywords:
- Osteomyelitis; Subacute Care; Surgical Procedures; Operative; Child
- 摘要:
- 亚急性骨髓炎多见于儿童和青少年,好发于四肢长骨干骺端,致病菌多为金黄色葡萄球菌或链球菌。该病通常起病隐匿,症状及体征轻微、不典型,炎性指标正常或轻度升高,因此容易误诊、漏诊,从而延误治疗。亚急性骨髓炎一旦确诊应予足疗程适宜抗生素保守治疗、手术刮除或二者联合使用,大部分患者疗效较好。本文就亚急性骨髓炎的流行病学特征、临床表现、诊断、治疗及预后进行综述,以实现亚急性骨髓炎更早期、更准确的诊断与治疗。
- Abstract:
- Subacute osteomyelitis is frequently encountered in children and adolescents,affecting epiphysis of long shaft of extremities.And the pathogenic bacteria are Staphylococcus aureus or Streptococcus.It often has an occult onset with mild and non-typical symptoms and signs.Parameters of laboratory examination are generally normal or slightly elevated.Therefore it is easily underdiagnosed and misdiagnosed so that treatment becomes delayed.Upon a definite diagnosis,conservative treatment with antibiotics,surgical curettage or the combination of the two is effective.Most patients have decent outcomes.This review summarized clinical epidemiological characteristics,clinical manifestations,proper managements and outcomes of subacute osteomyelitis to guide clinical practices.
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备注/Memo
收稿日期:2022-11-30。
基金项目:云南地区儿童骨关节感染性疾病致病菌及耐药性分布的研究(2022-04-07-004);云南省杨军林专家工作站(33042119850504759)
通讯作者:康晓鹏,Email:shedk@163.com