Deng Shuping,Zeng Yupei,Yuan Cuixia,et al.Diagnosis and treatment of chest wall tumors in children: A Single Center Surgical Experience[J].Journal of Clinical Pediatric Surgery,2022,21(03):220-224.[doi:10.3760/cma.j.cn101785-202202011-004]
儿童胸壁肿瘤的外科诊治:单中心经验分析
- Title:
- Diagnosis and treatment of chest wall tumors in children: A Single Center Surgical Experience
- Keywords:
- Thoracic Neoplasms/DI; Thoracic Neoplasms/TH; Thoracic Neoplasms/SU; Treatment Outcome; Child
- 摘要:
- 目的 总结儿童胸壁肿瘤的外科诊治经验，探讨儿童胸壁肿瘤的处理策略。方法 回顾性分析2011年1月至2021年12月于重庆医科大学附属儿童医院接受手术治疗的127例胸壁肿瘤患儿临床资料，其中男83例，女44例；年龄（45.62±19.13）个月（2天至16岁5个月）；体重（16.71±8.58） kg （3.5~83 kg）。所有患儿均接受手术治疗，术后定期随访，收集患儿手术及治疗结果信息。结果 127例中，胸壁原发肿瘤126例，转移性肿瘤1例。5例行肿瘤部分切除/活检术，1例行肿瘤扩大切除术，其余121例行肿瘤切除术。手术时间12~167 min，术中出血1~500 mL。病理结果显示良性肿瘤115例（90.6%），交界性肿瘤3例（2.4%），恶性肿瘤9例（7%）。8例恶性肿瘤患儿术后接受化疗和（或）放疗、靶向药物治疗。全组无一例手术死亡。121例患儿获得随访，随访时间（4.92±2.17）年（1个月至10年）。3例恶性肿瘤患儿因肿瘤远处转移死亡，其余病例均存活。随访期间肿瘤局部复发再手术6例。结论 儿童胸壁肿瘤临床较少见，绝大多数为良性肿瘤，手术治疗效果良好。儿童恶性胸壁肿瘤罕见，预后不良，有必要研究儿童恶性胸壁肿瘤评估、诊治的新方法。
- Abstract:
- Objective To summarize the experience of diagnosis and surgical treatment of chest wall tumor (CWT) in children and to explore its therapeutic strategies.Methods The clinical data of 127 children (83 males, 44 females) with CWT from January 2011 to December 2021 were analyzed retrospectively.Patients’ median age was 45.62±19.13 months, and average weight was 16.71±8.58 kg.All patients received surgical resection and were followed up regularly after operation.Results There were 126 cases of primary tumors and 1 case of metastatic tumor in the chest wall.Partial tumor resection/biopsy was performed in 5 cases, extended tumor resection in 1 case, and tumor resection in other 121 cases.The operation time was 12-167 min and the intraoperative blood loss was 1-500 mL.Pathological examination showed 115 cases of benign tumors (90.6%), 3 cases of borderline tumors (2.4%), and 9(7.0%) cases of malignant tumors (7%).Eight children with malignant tumors were treated with chemotherapy and/or radiotherapy and targeted drugs.No death occurred during the operation.6 patients dropped out and 121 children were followed up (4.92±2.17) years.3 children with malignant tumors died of distant metastasis, while the rest survived.There were 6 cases undergoing reoperation for local recurrence.Conclusion CWTs in children are hardly seen, but most of which are benign tumors, and have satisfactory surgical results Malignant CWTs in children are rare with poor prognosis.It is necessary to develop a new method for evaluating, diagnosing and treating malignant CWT in children.
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备注/Memo
收稿日期:2022-02-05。
基金项目:重庆市医学科研项目（2016ZDXM013）
通讯作者:李勇刚,Email:yulyg@sina.com