[1]林晟,黄雨珊,刘兰,等.腹膜后卵黄囊瘤伴肝转移1例[J].临床小儿外科杂志,2026,(01):89-91.[doi:10.3760/cma.j.cn101785-202307031]
　Lin Sheng,Huang Yushan,Liu Lan,et al.Retroperitoneal yolk sac tumor with liver metastasis: one case report[J].Journal of Clinical Pediatric Surgery,2026,(01):89-91.[doi:10.3760/cma.j.cn101785-202307031]
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腹膜后卵黄囊瘤伴肝转移1例

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 期数: 2026年01 页码: 89-91 栏目: 病例报告 出版日期: 2026-01-28
Title:
Retroperitoneal yolk sac tumor with liver metastasis: one case report
作者:
林晟;  黄雨珊;  刘兰;  白建喜;  张炳;  吴典明
福建省儿童医院 上海儿童医学中心福建医院普外科 福建医科大学妇儿临床医学院, 福州 350000
Author(s):
Lin Sheng;  Huang Yushan;  Liu Lan;  Bai Jianxi;  Zhang Bing;  Wu Dianming
Department of General Surgery, Fujian Children’s Hospital, Fujian Hospital, Shanghai Children’s Medical Center, College of Clinical Medicine for Women & Children, Fuzhou 350000, China
关键词:
腹膜后; 卵黄囊瘤; 肝转移
DOI:
10.3760/cma.j.cn101785-202307031
摘要:
生殖细胞肿瘤伴发肝转移临床罕见。本文报道1例2岁10月龄男童因腹部隆起4个月就诊,经检查诊断为腹膜后卵黄囊瘤伴肝转移。患儿术前予4周期化疗(含铂类方案)后行腹膜后肿物切除术,术中见肝转移灶无活性肿瘤成分。术后随访4个月,患儿甲胎蛋白降至正常,肝转移灶缩小,腹膜后无复发。

参考文献/References:

[1] 苏雁,洪慧敏,赵倩,等.纵隔生殖细胞肿瘤并发恶性血液病3例并文献复习[J].中华实用儿科临床杂志,2022,37(5):377-381.DOI:10.3760/cma.j.cn101070-20201012-01606. Su Y,Hong HM,Zhao Q,et al.Mediastinal germ cell tumors and concurrent hematologic malignancy:a report of 3 cases with a literature review[J].Chin J Appl Clin Pediatr,2022,37(5):377-381.DOI:10.3760/cma.j.cn101070-20201012-01606.
[2] Calaminus G,Joffe J.Germ cell tumors in adolescents and young adults[J].Prog Tumor Res,2016,43:115-127.DOI:10.1159/000447081.
[3] 施全,王凤华,高秋,等.儿童及青少年卵黄囊瘤的临床病理分析[J].中国妇幼健康研究,2019,30(3):342-346.DOI:10.3969/j.issn.1673-5293.2019.03.019. Shi Q,Wang FH,Gao Q,et al.Clinicopathological analysis of yolk sac tumor in children and adolescents[J].Chin J Woman Child Health Res,2019,30(3):342-346.DOI:10.3969/j.issn.1673-5293.2019.03.019.
[4] 许恬逸,董瑞.儿童卵黄囊瘤病因研究进展[J].临床小儿外科杂志,2021,20(12):1194-1200.DOI:10.12260/lcxewkzz.2021.12.018. Xu TY,Dong R.Research advances in etiology of yolk sac tumor in children[J].J Clin Ped Sur,2021,20(12):1194-1200.DOI:10.12260/lcxewkzz.2021.12.018.
[5] De Felici M,Klinger FG,Campolo F,et al.To be or not to be a germ cell:the extragonadal germ cell tumor paradigm[J].Int J Mol Sci,2021,22(11):5982.DOI:10.3390/ijms22115982.
[6] 陈吉,易军,孙斌,等.肝外型肝母细胞瘤一例[J].中华小儿外科杂志,2016,37(4):302-303.DOI:10.3760/cma.j.issn.0253-3006.2016.04.014. Chen J,Yi J,Sun B,et al.Extrahepatic hepatoblastoma:one case report[J].Chin J Pediatr Surg,2016,37(4):302-303.DOI:10.3760/cma.j.issn.0253-3006.2016.04.014.
[7] 朱帅,张大伟,苏雁,等.伴有肝脏受累的神经母细胞瘤患儿临床特点及预后分析——单中心10年诊治总结[J].中国小儿血液与肿瘤杂志,2019,24(4):186-191.DOI:10.3969/j.issn.1673-5323.2019.04.004. Zhu S,Zhang DW,Su Y,et al.Clinical characteristics and prognosis of neuroblastoma with liver involvement in children:10-year diagnostic & therapeutic experiences at a single center[J].J China Pediatr Blood Cancer,2019,24(4):186-191.DOI:10.3969/j.issn.1673-5323.2019.04.004.
[8] 杨双风,高军,李航,等.新生儿神经母细胞瘤的影像学表现[J].中国医学影像学杂志,2021,29(10):1028-1034.DOI:10.3969/j.issn.1005-5185.2021.10.015. Yang SF,Gao J,Li H,et al.Imaging features of neuroblastoma in neonates[J].Chin J Med Imaging,2021,29(10):1028-1034.DOI:10.3969/j.issn.1005-5185.2021.10.015.
[9] 张继军,王隽,苏明,等.卵巢成熟囊性畸胎瘤误诊或漏诊CT表现分析[J].实用放射学杂志,2017,33(12):1895-1897.DOI:10.3969/j.issn.1002-1671.2017.12.022. Zhang JJ,Wang J,Su M,et al.Analysis of CT manifestations of misdiagnosed or missed ovarian cystic mature teratomas[J].J Pract Radiol,2017,33(12):1895-1897.DOI:10.3969/j.issn.1002-1671.2017.12.022.
[10] 胡赢,韦成江,龚晗,等.结直肠癌肝转移灶的影像学特征与病理微形态学特点的关系[J].临床与实验病理学杂志,2022,38(9):1109-1112.DOI:10.13315/j.cnki.cjcep.2022.09.018. Hu Y,Wei CJ,Gong H,et al.Relationship between imaging features and pathological micromorphological characteristics of liver metastases in colorectal cancer[J].Chin J Clin Exp Pathol,2022,38(9):1109-1112.DOI:10.13315/j.cnki.cjcep.2022.09.018.
[11] International Germ Cell Consensus Classification:a prognostic factor-based staging system for metastatic germ cell cancers.International Germ Cell Cancer Collaborative Group[J].J Clin Oncol,1997,15(2):594-603.DOI:10.1200/JCO.1997.15.2.594.
[12] 宋君红,高怡瑾,潘慈,等.138例儿童颅外恶性生殖细胞肿瘤临床研究[J].现代肿瘤医学,2019,27(3):468-471.DOI:10.3969/j.issn.1672-4992.2019.03.027. Song JH,Gao YJ,Pan C,et al.Clinical observation of 138 children with extracranial malignant germ cell tumors[J].J Mod Oncol,2019,27(3):468-471.DOI:10.3969/j.issn.1672-4992.2019.03.027.

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[2]张虹,白建喜,张炳,等.儿童脐尿管卵黄囊瘤1例[J].临床小儿外科杂志,2024,23(07):689.[doi:10.3760/cma.j.cn101785-202203089-016]
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备注/Memo

收稿日期:2023-7-18。
基金项目:福建省儿童医院医疗创双高项目(ETK 2023014)
通讯作者:吴典明,Email:wudianming2023@163.com

更新日期/Last Update: 2026-01-28