Xie Yonghong,Tan Xiaoqian,Tan Qian,et al.Correlation analysis between imaging features of low-density lines and fracture risk in children of non-Crawford type Ⅳ congenital pseudarthrosis of the tibia[J].Journal of Clinical Pediatric Surgery,2025,(11):1047-1050.[doi:10.3760/cma.j.cn101785-202504049-010]
非Crawford Ⅳ型先天性胫骨假关节低密度线的影像学特征与骨折风险的关联性分析
- Title:
- Correlation analysis between imaging features of low-density lines and fracture risk in children of non-Crawford type Ⅳ congenital pseudarthrosis of the tibia
- 摘要:
- 目的 初步探讨非Crawford Ⅳ型CPT患儿低密度线的影像学特征,并分析其与骨折风险的关联性。方法 本研究为回顾性病例系列研究,以2015年1月至2020年12月湖南省儿童医院收治的106例CPT患儿为研究对象。收集患儿基线资料(性别、首诊年龄、首次发病年龄、患肢侧别、是否合并NF1、是否发生胫骨骨折,以及是否有明确的外伤史)、影像学资料(Crawford分型、低密度线分布及进展情况)以及治疗相关资料(手术治疗或保守治疗、低密度线发生前后的治疗情况)。结果 106例CPT患儿中,Crawford Ⅰ型27例、Crawford Ⅱ型47例、Crawford Ⅲ 型32例,无骨折组70例,骨折组36例;两组患儿有低密度线的人数比例(14/70比32/36)差异有统计学意义(P<0.05)。结论 低密度线在胫骨髓干横径的区域范围占比越大,其骨折发生风险越高,可作为预测骨折风险的重要参考指标。
- Abstract:
- Objective To explore the imaging characteristics of low-density lines in children of non-Crawford type Ⅳ CPT (congenital pseudarthrosis of the tibia) and analyze their association with fracture risk. Methods For this retrospective case series study,106 CPT children admitted from January 2015 to December 2020 were selected as research subjects.Baseline data (gender,age at an initial visit,age at an initial onset,affected extremity sideness,presence of NF1,occurrence of tibial fracture & a definite history of trauma),imaging data (Crawford classification,low-density line distribution & progression) and treatment-related details (surgical or conservative treatment,treatment before and after low-density line occurring) were recorded. Results The clinical types were Crawford Ⅰ(n=27),Crawford Ⅱ(n=47),Crawford Ⅲ(n=32).Among 106 non Crawford type Ⅳ cases,there were 70 cases in non fracture group and 36 cases in fracture group.Statistically significant inter-group difference existed in the proportion of children with low-density lines (14/70 vs. 32/36) (P<0.05). Conclusions The larger the proportion of low-density lines in transverse diameter of tibial bone marrow,the higher the risk of fracture occurrence.It may be employed as an important reference indicator for predicting fracture risk.
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备注/Memo
收稿日期:2025-4-18。
基金项目:国家临床重点专科重大科研专项(Z2023057);湖南省卫生健康委卫生科研课题(W20243208);儿童骨科学湖南省重点实验室(2023TP1019);长沙市自然科学基金项目(kq2502165)
通讯作者:杨戈,Email:yangge@zju.edu.cn