[1]刘鑫,杨屹.从指南到实践:对于儿童肾母细胞瘤治疗规范的几点思考[J].临床小儿外科杂志,2025,(10):901-904.[doi:10.3760/cma.j.cn101785-202507007-001]
　Liu Xin,Yang Yi.From guidelines to practice: Reflections on standardizing treatments of Wilms tumor in children[J].Journal of Clinical Pediatric Surgery,2025,(10):901-904.[doi:10.3760/cma.j.cn101785-202507007-001]
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从指南到实践:对于儿童肾母细胞瘤治疗规范的几点思考

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 期数: 2025年10 页码: 901-904 栏目: 述评 出版日期: 2025-10-28
Title:
From guidelines to practice: Reflections on standardizing treatments of Wilms tumor in children
作者:
刘鑫;  杨屹
中国医科大学附属盛京医院小儿泌尿外科, 沈阳 110004
Author(s):
Liu Xin;  Yang Yi
Department of Pediatric Urology, Affiliated Shengjing Hospital, China Medical University, Shenyang 110004, China
关键词:
Wilms瘤; 治疗; 诊疗指南; 循证实践; 思考
Keywords:
Wilms Tumor; Therapy; Diagnostic and treatment guideline; Evidence-Based Practice; Thinking
DOI:
10.3760/cma.j.cn101785-202507007-001
摘要:
肾母细胞瘤是儿童最常见的肾脏肿瘤。目前,通过手术联合辅助/新辅助化疗及必要时放疗的综合治疗,肾母细胞瘤患儿总体生存率得以显著提高。尽管多数患儿预后良好,但仍有部分患儿面临生存率低或治疗相关长期不良反应的风险。这些风险除与肿瘤的生物学特征有关以外,也和临床治疗不规范相关。本文结合国内外相关文献和笔者临床体会,对相关肾母细胞瘤规范治疗的争议问题进行系统阐述,供读者参考和指正。
Abstract:
Wilms tumor (WT) is the most common kidney tumor in children.Thanks to comprehensive protocols involving surgery plus adjuvant/neoadjuvant chemoradiotherapy when necessary,the overall survival rate of WT children has significantly improved.Despite a generally favorable prognosis for most cases,some still face the risks of lower survival rates or long-term treatment-related side effects.These risks are related not only to tumor’s inherent biological characteristics but also non-standardized clinical treatment practices.This review systematically addressed several controversial issues concerning the standardized treatment of WT,drawing upon the relevant domestic and foreign literature and personal clinical experience for readers’ references and comments.

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备注/Memo

收稿日期:2025-7-4。
通讯作者:杨屹,Email:yangy2@sj-hospital.org

更新日期/Last Update: 2025-10-28