Lan Menglong,Zeng Jixiao,Xu Xiaogang,et al.Application of robotic-assisted surgery in reoperation of Hirschsprung’s disease:a single-center experience[J].Journal of Clinical Pediatric Surgery,2025,(06):512-518.[doi:10.3760/cma.j.cn101785-202408051-003]
机器人手术在巨结肠根治术后再手术中的应用:单中心经验
- Title:
- Application of robotic-assisted surgery in reoperation of Hirschsprung’s disease:a single-center experience
- 关键词:
- Hirschsprung病; 手术后并发症; 再手术; 机器人辅助腹腔镜手术; 儿童
- Keywords:
- Hirschsprung Disease; Postoperative Complications; Reoperation; Robotic-assisted Redo Pull-through Procedure; Child
- 摘要:
- 目的 评估巨结肠根治术后因并发症行机器人辅助再手术(robotic-assisted redo pull-through procedure,RARPT)的安全性及有效性,分析再手术的原因,总结手术经验。方法 回顾性分析2022年11月至2024年7月于广州医科大学附属妇女儿童医疗中心胃肠外科因巨结肠根治术后并发症而行RARPT的16例患儿临床资料。其中男10例、女6例;再次手术原因:便秘复发7例(获得性无神经节细胞1例、肌鞘残留2例、病变肠管残留4例),吻合口瘘6例(直肠阴道瘘2例,其他吻合口瘘4例),吻合口狭窄3例。RARPT具体手术方式包括Deloyers术7例,Swenson术7例(包括同时行残留肌鞘切除2例,吻合口瘘周围瘢痕肉芽组织清除5例),Swenson术+直肠阴道瘘修补术2例。结果 中位手术时间为315(200~510)min,出血量均小于20 mL,术后恢复饮食时间2~7 d,术后首次肛门排便时间1~3 d,术后住院时间8~14 d,术中无严重并发症出现,无一例中转开腹手术。1例住院期间出现不完全性肠梗阻,经保守治疗后好转出院。术后随访2~21个月,1例曾因不完全性肠梗阻经保守治疗痊愈,1例出现小肠结肠炎,经回流灌肠后好转,6例存在污粪现象。结论 RARPT治疗巨结肠根治术后并发症的安全性及有效性良好,近期效果满意。
- Abstract:
- Objective To evaluate the safety and effectiveness of robotic-assisted redo pull-through procedure (RAPT) due to complications after primary pull-through procedure (PT) for Hirschsprung’s disease (HSCR),examine the reasons for reoperation and summarize surgical experiences. Methods From November 2022 to July 2024,the relevant clinical data were retrospectively reviewed for 16 children undergoing RARPT for complications after primary PT for HSCR.There were 10 boys and 6 girls.The reasons for reoperation included recurrence of constipation (n=7) (acquired aganglionosis,n=1; residual rectal muscle cuff,n=2; residual aganglionic segment or transitional zone,n=4) and anastomotic fistula (n=6)(rectovaginal fistula,n=2; anastomotic stenosis,n=3).Reoperative approaches of RAPPT included Deloyers procedure (n=7),Swenson procedure (n=7) (simultaneous residual muscle sheath resection,n=2; removal of scar granulation tissue around anastomotic fistula,n=5) and Swenson procedure with repair of rectovaginal fistula (n=2). Results The median operative duration was 315(200-510) min,bleeding volume less than 20 ml,postoperative recovery time for eating and drinking (2-7) day,initial postoperative defecation time (1-3) day and postoperative hospital stay (8-14) day.No serious intraoperative complications occurred and there was no conversion into laparotomy.One child of incomplete intestinal obstruction improved after conservative measures and was discharged.Postoperative follow-up period was (2-21) month.One child was re-hospitalized for incomplete intestinal obstruction.Another case of enterocolitis improved after enema.There were 6 cases of soiling. Conclusions RARPT is both safe and effective for postoperative complications of HSCR.
参考文献/References:
[1] Montalva L,Cheng LS,Kapur R,et al.Hirschsprung disease[J].Nat Rev Dis Primers,2023,9(1):54.DOI:10.1038/s41572-023-00465-y.
[2] 曾纪晓,徐晓钢,王欣星,等.达芬奇机器人辅助Swenson-like巨结肠根治术[J].中华腔镜外科杂志(电子版),2024,17(4):239-243.DOI:10.3877/cma.j.issn.1674-6899.2024.04.009. Zeng JX,Xu XG,Wang XX,et al.Da Vinci robotic-assisted Swenson-like pull through for Hirschsprung’s disease[J].Chin J Laparosc Surg (Electronic Edition),2024,17(4):239-243.DOI:10.3877/cma.j.issn.1674-6899.2024.04.009.
[3] Pini Prato A,Arnoldi R,Dusio MP,et al.Totally robotic soave pull-through procedure for Hirschsprung’s disease:lessons learned from 11 consecutive pediatric patients[J].Pediatr Surg Int,2020,36(2):209-218.DOI:10.1007/s00383-019-04593-z.
[4] Zhang MX,Zhang X,Chi SQ,et al.Robotic-assisted proctosigmoidectomy versus laparoscopic-assisted soave pull-through for Hirschsprung disease:medium-term outcomes from a prospective multicenter study[J].Ann Surg,2025,281(4):689-697.DOI:10.1097/SLA.0000000000006172.
[5] Mottadelli G,Erculiani M,Casella S,et al.Robotic surgery in Hirschsprung disease:a unicentric experience on 31 procedures[J].J Robot Surg,2023,17(3):897-904.DOI:10.1007/s11701-022-01488-5.
[6] Thomson D,Allin B,Long AM,et al.Laparoscopic assistance for primary transanal pull-through in Hirschsprung’s disease:a systematic review and meta-analysis[J].BMJ Open,2015,5(3):e006063.DOI:10.1136/bmjopen-2014-006063.
[7] Yokota K,Uchida H,Tainaka T,et al.Single-stage laparoscopic transanal pull-through modified Swenson procedure without leaving a muscular cuff for short- and long-type Hirschsprung disease:a comparative study[J].Pediatr Surg Int,2018,34(10):1105-1110.DOI:10.1007/s00383-018-4318-1.
[8] Tomuschat C,Zimmer J,Puri P.Laparoscopic-assisted pull-through operation for Hirschsprung’s disease:a systematic review and meta-analysis[J].Pediatr Surg Int,2016,32(8):751-757.DOI:10.1007/s00383-016-3910-5.
[9] 兰梦龙,曾纪晓,徐晓钢,等.先天性巨结肠术后便秘复发再手术19例[J].临床小儿外科杂志,2021,20(3):230-235.DOI:10.12260/lcxewkzz.2021.03.006. Lan ML,Zeng JX,Xu XG,et al.Redo pull-through for Hirsch-sprung’s disease with recurrent postoperative constipation[J].DOI:10.12260/lcxewkzz.2021.03.006.
[10] 李颀,张震,肖萍,等.再次手术治疗先天性巨结肠初次根治术后中远期并发症的临床研究[J].中华小儿外科杂志,2021,42(7):639-645.DOI:10.3760/cma.j.cn421158-20200309-00153. Li Q,Zhang Z,Xiao P,et al.Redo pull-through for late postoperative complications of Hirschsprung’s disease[J].Chin J Pediatr Surg,2021,42(7):639-645.DOI:10.3760/cma.j.cn421158-20200309-00153.
[11] 曾纪晓.先天性巨结肠非计划性再手术的相关问题[J].临床小儿外科杂志,2018,17(2):94-98.DOI:10.3969/j.issn.1671-6353.2018.02.004. Zeng JX.Related issues of unscheduled re-operation for Hirschsprung’s disease[J].J Clin Ped Sur,2018,17(2):94-98.DOI:10.3969/j.issn.1671-6353.2018.02.004.
[12] Peng CH,Chen YJ,Pang WB,et al.Redo transanal soave pull through with or without assistance in Hirschsprung disease:an experience in 46 patients[J].Eur J Pediatr Surg,2021,31(2):182-186.DOI:10.1055/s-0040-1710028.
[13] Ullrich S,Denning NL,Holder M,et al.Does length of extended resection beyond transition zone change clinical outcome for Hirschsprung pull-through?[J].J Pediatr Surg,2024,59(1):86-90.DOI:10.1016/j.jpedsurg.2023.09.024.
[14] 徐晓钢,曾纪晓,刘斐,等.单孔腹腔镜Deloyers术在先天性长段型巨结肠一期根治术中的应用[J].中华小儿外科杂志,2023,44(1):13-17.DOI:10.3760/cma.j.cn421158-20220111-00026. Xu XG,Zeng JX,Liu F,et al.Application of single-port Deloyers laparoscopy in one-stage radical operation for Hirschsprung disease[J].Chin J Pediatr Surg,2023,44(1):13-17.DOI:10.3760/cma.j.cn421158-20220111-00026.
[15] Ostertag-Hill CA,Nandivada P,Dickie BH.Late diagnosis of Hirschsprung disease:clinical presentation and long-term functional outcomes[J].J Pediatr Surg,2024,59(2):220-224.DOI:10.1016/j.jpedsurg.2023.10.018.
[16] 徐晓钢,曾纪晓,刘斐,等.吲哚菁绿荧光血管显像技术在单孔腹腔镜巨结肠根治术中的应用[J].中国微创外科杂志,2021,21(2):165-168.DOI:10.3969/j.issn.1009-6604.2021.02.015. Xu XG,Zeng JX,Liu F,et al.Application of indocyanine green fluorescence angiography in single-port laparoscopic radical operation for Hirschsprung’s disease[J].Chin J Min Inv Surg,2021,21(2):165-168.DOI:10.3969/j.issn.1009-6604.2021.02.015.
[17] 徐晓钢,曾纪晓,刘斐,等.腹腔镜吲哚菁绿荧光导航下精准保留脾血管胰尾切除治疗儿童实性假乳头状瘤[J].中华腔镜外科杂志(电子版),2022,15(4):245-248.DOI:10.3877/cma.j.issn.1674-6899.2022.04.012. Xu XG,Zeng JX,Liu F,et al.Laparoscopic splenic vessels-preserving distal pancreatectomy accurately for solid pseudopapillary neoplasm in children with indocyanine green fluorescence navigation technique[J].Chin J Laparosc Surg (Electronic Edition),2022,15(4):245-248.DOI:10.3877/cma.j.issn.1674-6899.2022.04.012.
[18] Li Q,Zhang Z,Xiao P,et al.Surgical approach and functional outcome of redo pull-through for postoperative complications in Hirschsprung’s disease[J].Pediatr Surg Int,2021,37(10):1401-1407.DOI:10.1007/s00383-021-04965-4.
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备注/Memo
收稿日期:2024-8-31。
基金项目:国家自然科学基金(82170528);广东省自然科学基金(2022A1515012254);广州市科技计划市校(院)联合资助项目(202201010612、2023A03J0865);广州地区临床特色技术项目(2023C-TS48);卫生健康技术重点推广项目(XM202403895)
通讯作者:曾纪晓,Email:zengjixiao@163.com