Leng Han,Huang Jin,Zhang Chen,et al.Research progress on anterior spinal overgrowth in adolescent idiopathic scoliosis[J].Journal of Clinical Pediatric Surgery,2024,(10):997-1000.[doi:10.3760/cma.j.cn101785-202302024-019]
青少年特发性脊柱侧弯脊柱前部过度生长的研究进展
- Title:
- Research progress on anterior spinal overgrowth in adolescent idiopathic scoliosis
- 关键词:
- 青少年特发性脊柱侧弯; 脊柱前部过度生长; 椎体; 椎间盘
- Keywords:
- Adolescent Idiopathic Scoliosis; Relative Anterior Spinal Overgrowth; Vertebra; Intervertebral Disc
- 摘要:
- 青少年特发性脊柱侧弯(adolescent idiopathic scoliosis, AIS)是一种常见于女性的复杂脊柱三维畸形。探索AIS的发生、发展机制是治疗该病的关键。脊柱前部过度生长(relative anterior spinal overgrowth, RASO)被认为在AIS的发生发展过程中起到至关重要的作用。脊柱前部相对生长速度加快以及不对称元素的潜在变化, 可以诱导脊柱侧弯的发生发展, 并伴随脊柱侧弯的进展而恶化, 这是导致AIS的关键因素。本文就AIS与RASO的相关性研究进展进行综述, 为AIS的临床及科研工作提供参考。
- Abstract:
- Adolescent idiopathic scoliosis (AIS) is a common complex three-dimensional spinal deformity that predominantly affects females.Understanding the mechanisms of the onset and progression of AIS is crucial for its treatment.Relative anterior spinal overgrowth (RASO) is believed to play a crucial role in the development of AIS.Accelerated relative growth of the anterior spine and potential asymmetrical changes in elements can induce the onset and progression of spinal curvature, which worsens with the progression of scoliosis, making it a key factor in the development of AIS.This review summarizes the research progress on the correlation between AIS and RASO, providing reference for clinical and research work on AIS.
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备注/Memo
收稿日期:2023-2-16。
基金项目:甘肃省自然科学基金(22JR5RA632);甘肃省联合科研基金重大项目(23JRRA1529)
通讯作者:何勇,Email:1774898257@qq.com